Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

Nuclear factor κB (NF-κB) transcription factors have a key role in many physiological
processes such as innate and adaptive immune responses, cell proliferation, cell death, and …

Abundant data support a key role for the transcription factor nuclear factor-κB (NF-κB)
signaling pathway in controlling the initiation and progression of human cancer. NF-κB and …

During their lifetime, cells encounter many life or death situations that challenge their very
own existence. Their survival depends on the interplay within a complex yet precisely …

Breast cancer is one of the leading causes of mortality in the females. Intensive efforts have
been made to understand the molecular mechanisms of pathogenesis of breast cancer. The …

Toll-like receptors (TLRs) are a family of transmembrane pattern recognition receptors
(PRR) that play a key role in innate and adaptive immunity by recognizing structural …

Background Naringenin, a flavonoid compound, has a wide variety of uses in the
pharmaceutical industry for its antioxidant and anti-inflammatory potential. Objectives The …

Introduction: Neutrophil extracellular trap (NET) formation was recently identified as a novel
mechanism to kill pathogens. However, excessive NET formation in sepsis can injure host …

To characterize the transcriptional program that governs terminal granulocytic differentiation
in vivo, we performed comprehensive microarray analyses of human bone marrow …

The ability to specifically label proteins with a wide range of optical properties and
functionalities can help reveal information about protein functions and dynamics in living …