Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …

Anaplastic thyroid cancer (ATC) is an infrequent thyroid tumor that usually occurs in elderly
patients. There is often a history of previous differentiated thyroid cancer suggesting a …

Background: The aim of this study was to describe the oncologic outcomes of patients with
BRAFV600E-mutated anaplastic thyroid cancer (ATC) who had neoadjuvant BRAF-directed …

PURPOSE Anaplastic thyroid carcinoma (ATC) uniformly present with aggressive disease,
but the mutational landscape of tumors varies. We aimed to determine whether tumor …

Introduction BRAF is a confirmed therapeutic target in non–small cell lung cancer (NSCLC),
as the BRAF inhibitor dabrafenib, in combination with the MEK inhibitor trametinib, is …

Iodine-resistant cancers account for the vast majority of thyroid related mortality and, until
recently, there were limited therapeutic options. However, over the last decade our …

Background: BRAFV600E and N/H/K RAS mutations and oncogenic kinase fusions
involving neurotrophin tyrosine receptor kinase (NTRK), RET, anaplastic lymphoma kinase …

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The treatment of advanced, radioiodine refractory, differentiated thyroid cancers (RR-DTCs)
has undergone major advancements in the last decade, causing a paradigm shift in the …

Thyroid cancer is the most common endocrine malignancy, the incidence of which has
increased significantly over the past decades. Advanced thyroid cancers, especially locally …