NLRP3 inflammasome in endothelial dysfunction

B Bai, Y Yang, QI Wang, M Li, C Tian, Y Liu… - Cell death & …, 2020 - nature.com
Inflammasomes are a class of cytosolic protein complexes. They act as cytosolic innate
immune signal receptors to sense pathogens and initiate inflammatory responses under …

Noncoding RNAs in vascular diseases

N Jaé, S Dimmeler - Circulation research, 2020 - Am Heart Assoc
The advent of deep sequencing technologies led to the identification of a considerable
amount of noncoding RNA transcripts, which are increasingly recognized for their functions …

The human-specific and smooth muscle cell-enriched LncRNA SMILR promotes proliferation by regulating mitotic CENPF mRNA and drives cell-cycle progression …

AD Mahmoud, MD Ballantyne, V Miscianinov… - Circulation …, 2019 - Am Heart Assoc
Rationale: In response to blood vessel wall injury, aberrant proliferation of vascular smooth
muscle cells (SMCs) causes pathological remodeling. However, the controlling mechanisms …

Non-coding RNA in thyroid cancer-Functions and mechanisms

J Cao, M Zhang, L Zhang, J Lou, F Zhou, M Fang - Cancer letters, 2021 - Elsevier
Thyroid cancer is the most common endocrine malignant tumor, and its incidence has
increased significantly in the past few years. A growing number of noncoding RNAs …

Emerging role of long non-coding RNAs in diabetic vascular complications

VS Tanwar, MA Reddy, R Natarajan - Frontiers in endocrinology, 2021 - frontiersin.org
Chronic metabolic disorders such as obesity and diabetes are associated with accelerated
rates of macrovascular and microvascular complications, which are leading causes of …

Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

C Bär, S Chatterjee, I Falcão Pires… - Cardiovascular …, 2020 - academic.oup.com
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …

[HTML][HTML] Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

X Cheng, MSSH Ali, M Moran, MP Viana, SL Schlichte… - Redox Biology, 2021 - Elsevier
Obesity-induced insulin resistance is a risk factor for diabetes and cardiovascular disease.
However, the mechanisms underlying endothelial senescence in obesity, and how it impacts …

Comparison of expression profiling of circular RNAs in vitreous humour between diabetic retinopathy and non-diabetes mellitus patients

M He, W Wang, H Yu, D Wang, D Cao, Y Zeng, Q Wu… - Acta …, 2020 - Springer
Aims To compare circular (circRNA) expression levels in the vitreous humour between PDR
(proliferative diabetic retinopathy) and the control groups. Methods The present study …

Non-coding RNAs and exosomal non-coding RNAs in traumatic brain injury: the small player with big actions

O Mohamadzadeh, M Hajinouri, F Moammer… - Molecular …, 2023 - Springer
Nowadays, there is an increasing concern regarding traumatic brain injury (TBI) worldwide
since substantial morbidity is observed after it, and the long-term consequences that are not …

LncRNA Neat1/miR-298-5p/Srpk1 contributes to sevoflurane-induced neurotoxicity

X Wei, S Xu, L Chen - Neurochemical research, 2021 - Springer
Sevoflurane is a widely used volatile anesthetic, that can cause long-term neurotoxicity and
learning and memory impairment. Long non-coding RNAs (lncRNAs) have been …