[HTML][HTML] Adenosine receptors: Emerging non-opioids targets for pain medications

SM Jung, L Peyton, H Essa, DS Choi - Neurobiology of Pain, 2022 - Elsevier
Physical and emotional pain deteriorates the quality of well-being. Also, numerous non-
invasive and invasive treatments for diagnosed diseases such as cancer medications and …

Locomotion activates PKA through dopamine and adenosine in striatal neurons

L Ma, J Day-Cooney, OJ Benavides, MA Muniak, M Qin… - Nature, 2022 - nature.com
The canonical model of striatal function predicts that animal locomotion is associated with
the opposing regulation of protein kinase A (PKA) in direct and indirect pathway striatal …

[HTML][HTML] Chemogenetics drives paradigm change in the investigation of behavioral circuits and neural mechanisms underlying drug action

A Ozawa, H Arakawa - Behavioural brain research, 2021 - Elsevier
Recent developments in chemogenetic approaches to the investigation of brain function
have ushered in a paradigm change in the strategy for drug and behavior research and …

Striatopallidal cannabinoid type-1 receptors mediate amphetamine-induced sensitization

Y Mariani, A Covelo, RS Rodrigues, F Julio-Kalajzić… - Current Biology, 2023 - cell.com
Repeated exposure to psychostimulants, such as amphetamine, causes a long-lasting
enhancement in the behavioral responses to the drug, called behavioral sensitization. 1 This …

Smartphone-based dual inverse signal MOFs fluorescence sensing for intelligent on-site visual detection of malachite green

L Jiang, C Li, X Hou - Talanta, 2024 - Elsevier
The development of intelligent, sensitive, and visual methods for the rapid detection of
veterinary drug residues is essential to ensure food quality and safety. Here, a smartphone …

The role of purinergic receptors in neural repair and regeneration after spinal cord injury

RD Cheng, W Ren, BY Luo, XM Ye - Neural Regeneration …, 2023 - journals.lww.com
Spinal cord injury is a serious injury of the central nervous system that results in neurological
deficits. The pathophysiological mechanisms underlying spinal cord injury, as well as the …

NF1-cAMP signaling dissociates cell type–specific contributions of striatal medium spiny neurons to reward valuation and motor control

LP Sutton, BS Muntean, O Ostrovskaya, S Zucca… - PLoS …, 2019 - journals.plos.org
The striatum plays a fundamental role in motor learning and reward-related behaviors that
are synergistically shaped by populations of D1 dopamine receptor (D1R)-and D2 …

The Pathophysiology of Tics: An Anatomic Review

HS Singer, J Pellicciotti - Psychiatric Clinics, 2024 - psych.theclinics.com
Tourette syndrome (TS) is a common neuropsychiatric disorder characterized by the
presence of chronic motor and phonic tics. The goal of this article is to review our current …

Ligands of the neuropeptide Y Y2 receptors as a potential multitarget therapeutic approach for the protection of the neurovascular unit against acute ischemia …

Ł Przykaza, E Kozniewska - Translational Stroke Research, 2022 - Springer
Ischemic stroke is the third leading cause of death and disability worldwide, with no
available satisfactory prevention or treatment approach. The current treatment is limited to …

Biophysical Dissection of Isolated GPCRs: The Adenosine A2A Receptor under the Bistouries

JL Banères, T Botzanowski, JA Boutin, B Calamini… - Receptors, 2023 - mdpi.com
In an effort to provide an overview of the biophysical approaches used to study G-protein-
coupled receptors, we chose to consider the adenosine A2A receptor as a model, as it is …