[HTML][HTML] Recent advances in CAR-based solid tumor immunotherapy

MH Shin, E Oh, Y Kim, DH Nam, SY Jeon, JH Yu… - Cells, 2023 - mdpi.com
Adoptive cell therapy using chimeric antigen receptor (CAR) technology is one of the most
advanced engineering platforms for cancer immunotherapy. CAR-T cells have shown …

[HTML][HTML] Advancements in CAR-NK therapy: lessons to be learned from CAR-T therapy

MK Kilgour, DJ Bastin, SH Lee, M Ardolino… - Frontiers in …, 2023 - frontiersin.org
Advancements in chimeric antigen receptor engineered T-cell (CAR-T) therapy have
revolutionized treatment for several cancer types over the past decade. Despite this success …

Polymer micropatches as natural killer cell engagers for tumor therapy

S Prakash, N Kumbhojkar, A Lu, N Kapate, VC Suja… - ACS …, 2023 - ACS Publications
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to
various cancers. Their efficacy, however, is limited by their low persistence and anergy …

[HTML][HTML] Evolution of cell therapy for renal cell carcinoma

Y Wang, ER Suarez, G Kastrunes, NSP de Campos… - Molecular Cancer, 2024 - Springer
Abstract Treatment for renal cell carcinoma (RCC) has improved dramatically over the last
decade, shifting from high-dose cytokine therapy in combination with surgical resection of …

[HTML][HTML] Cytokine‐Induced Memory‐Like NK Cells: Emerging strategy for AML immunotherapy

M Bakhtiyaridovvombaygi, S Yazdanparast… - Biomedicine & …, 2023 - Elsevier
Acute myeloid leukemia (AML) is a heterogeneous disease developed from the malignant
expansion of myeloid precursor cells in the bone marrow and peripheral blood. The …

[HTML][HTML] The power and the promise of CAR-mediated cell immunotherapy for clinical application in pancreatic cancer

HY Tang, YZ Cao, YW Zhou, YS Ma, H Jiang… - Journal of Advanced …, 2024 - Elsevier
Background Pancreatic cancer, referred to as the “monarch of malignancies,” is a neoplastic
growth mostly arising from the epithelial cells of the pancreatic duct and acinar cells. This …

Dysfunctional natural killer cells can be reprogrammed to regain anti-tumor activity

B Sabag, A Puthenveetil, M Levy, N Joseph… - The EMBO …, 2024 - embopress.org
Natural killer (NK) cells are critical to the innate immune system, as they recognize antigens
without prior sensitization, and contribute to the control and clearance of viral infections and …

[HTML][HTML] Intrinsic and extrinsic factors determining natural killer cell fate: Phenotype and function

L Zhi, X Wang, Q Gao, W He, C Shang, C Guo… - Biomedicine & …, 2023 - Elsevier
Natural killer (NK) cells are derived from hematopoietic stem cells. They belong to the innate
lymphoid cell family, which is an important part of innate immunity. This family plays a role in …

[HTML][HTML] Potentiation of natural killer cells to overcome cancer resistance to NK cell-based therapy and to enhance antibody-based immunotherapy

M Fantini, PM Arlen, KY Tsang - Frontiers in Immunology, 2023 - frontiersin.org
Natural killer (NK) cells are cellular components of the innate immune system that can
recognize and suppress the proliferation of cancer cells. NK cells can eliminate cancer cells …

An Injectable Puerarin Depot Can Potentiate Chimeric Antigen Receptor Natural Killer Cell Immunotherapy Against Targeted Solid Tumors by Reversing Tumor …

Y Liu, Y Hao, J Chen, M Chen, J Tian, X Lv, Y Zhang… - Small, 2024 - Wiley Online Library
Chimeric antigen receptor natural killer (CAR‐NK) cell therapy represents a potent approach
to suppressing tumor growth because it has simultaneously inherited the specificity of CAR …