Biosynthesis of the triterpenoid withanolides in Withania somnifera

AK Narayanan, DA Nagegowda - Current Opinion in Plant Biology, 2024 - Elsevier
Abstract Ashwagandha (Withania somnifera L. Dunal) is a versatile medicinal plant of
Solanaceae family, renowned for its potent therapeutic properties, due to which it is …

Clinical pharmacokinetic evaluation of Withania somnifera (L.) Dunal root extract in healthy human volunteers: A non-randomized, single dose study utilizing UHPLC …

VG Vaidya, NN Naik, G Ganu, V Parmar… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Withania somnifera (L.) Dunal;(Solanaceae), commonly
known as Ashwagandha, is one of the most significant medicinal herbs in 'Ayurveda', a …

[HTML][HTML] Covalent binding of withanolides to cysteines of protein targets

C Bailly - Biochemical Pharmacology, 2024 - Elsevier
Withanolides represent an important category of natural products with a steroidal lactone
core. Many of them contain an α, β-unsaturated carbonyl moiety with a high reactivity toward …

Neuropsychopharmacological Induction of (Lucid) Dreams: A Narrative Review

AA Oldoni, AD Bacchi, FR Mendes, PA Tiba… - Brain Sciences, 2024 - mdpi.com
Lucid dreaming (LD) is a physiological state of consciousness that occurs when dreamers
become aware that they are dreaming, and may also control the oneiric content. In the …

Adaptogenic Botanicals with Emphasis on Rhodiola rosea and Withania somnifera

RP Machín, M Florido… - … of Medicinal Plants, 2023 - public.paper4promo.com
This review addresses the issue of plant adaptogens, botanical products with remarkable
anti-stress effects. These actions result from its ability to increase the non-specific organism's …

[PDF][PDF] Acid curd (Karish) cheese supplemented with ashwagandha and/or probiotics: Modulatory efficiency on induced behavioral and neurochemical changes in rats

HH Salama, KG Abdel-Wahhab, HMA Khalil… - health, 2024 - jfrm.ru
Neurodegenerative disorder leads to a progressive memory loss that has only limited known
medications. The use of ashwagandha, probiotics, or their combination may improve …

A review: Phytochemicals and bioactivities of Ashwagandha (Withania somnifera).

A Malik, N Raghav, N Mor - Chemistry & Biology Interface, 2024 - search.ebscohost.com
Ashwagandha is scientifically known as Withania somnifera (WS); a crucial medicinal plant
reported in the Indian traditional medicinal system, Ayurveda. It possesses a diverse range …

[PDF][PDF] Unveiling the Potentials of Withania somnifera (L.) Dunal as a Precise Therapeutic Intervention Against Glioblastoma Multiforme

S Kulavi, D Dhar, K Iyer, AK Ghosh, J Bandyopadhyay - 2024 - researchgate.net
Glioblastoma multiforme (GBM) is the most severe and fatal form of brain tumor, leading to a
poor survival rate in patients and making a significant contribution to cancer-related deaths …

Herbs for Autoimmune Diseases

A Mukne, S Dangat, P Shirodkar, K Sawate - Role of Herbal Medicines …, 2024 - Springer
The incidence of autoimmune diseases worldwide is on the rise, with extensive impact on
lifestyle of individuals and spiralling healthcare costs. Phytotherapies are increasingly being …

Shoden Promotes Relief from Stress and Anxiety: A Randomized, Double-Blind, Placebo-Controlled Study on Healthy Subjects with High Stress Levels

DN Mishra, M Kumar - 2023 - researchsquare.com
Background This randomized placebo-controlled study examined the effect of ashwagandha
root and leaf extract 60mg (AE60) and 120 mg (AE120)(35% withanolide glycosides …