This review traces the discoveries that led to the recognition of selenium (Se) as an essential
nutrient and discusses Se-responsive diseases in animals and humans in the context of …

Objective In this review, we have highlighted the advances over the past year in genetics,
genomics and epigenetics in the field of osteoarthritis (OA). Methods A literature search of …

Osteoarthritis (OA) is the most common form of arthritis in the adult population and is a
leading cause of disability. OA-related genetic loci may play an important role in clinical …

Objective Cartilage epigenetic changes are strongly associated with human osteoarthritis
(OA). However, the influence of individual environmental OA risk factors on these epigenetic …

Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy that exhibits
some similar characteristics to osteoarthritis (OA) but with different etiologies and …

Objectives Single-cell and spatial transcriptomics analysis of human knee articular cartilage
tissue to present a comprehensive transcriptome landscape and osteoarthritis (OA)-critical …

The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being
obesity, age, environmental variables, and genetic predisposition. The available evidence …

Osteoarthritis (OA) is a major contributor to disability and social costs in the elderly. As the
population ages and becomes increasingly obese, the incidence of the disease is higher …

Viral infections, including SARS-CoV-2, are accompanied by signs of systemic inflammation,
which can cause long-term sequela for the patient. Time-stable changes in the organism …

Osteoarthritis (OA) is a chronic, degenerative, musculoskeletal disease that is the leading
cause of disability in the United States. OA affects over 32 million adults in the US resulting …