Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
Acute myeloid leukaemia
CD DiNardo, HP Erba, SD Freeman, AH Wei - The Lancet, 2023 - thelancet.com
Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The
past decade has witnessed an increasingly improved scientific understanding of the …
past decade has witnessed an increasingly improved scientific understanding of the …
Towards precision medicine for AML
With rapid advances in sequencing technologies, tremendous progress has been made in
understanding the molecular pathogenesis of acute myeloid leukaemia (AML), thus …
understanding the molecular pathogenesis of acute myeloid leukaemia (AML), thus …
Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia
EJ Duncavage, A Bagg, RP Hasserjian… - Blood, The Journal …, 2022 - ashpublications.org
Myeloid neoplasms and acute leukemias derive from the clonal expansion of hematopoietic
cells driven by somatic gene mutations. Although assessment of morphology plays a crucial …
cells driven by somatic gene mutations. Although assessment of morphology plays a crucial …
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …
A review of FLT3 inhibitors in acute myeloid leukemia
JC Zhao, S Agarwal, H Ahmad, K Amin, JP Bewersdorf… - Blood reviews, 2022 - Elsevier
FLT3 mutations are the most common genetic aberrations found in acute myeloid leukemia
(AML) and associated with poor prognosis. Since the discovery of FLT3 mutations and their …
(AML) and associated with poor prognosis. Since the discovery of FLT3 mutations and their …
Prognostic Value of FLT3-Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia
T Grob, MA Sanders, CM Vonk… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The applicability of FLT3-internal tandem duplications (FLT3-ITD) for assessing
measurable residual disease (MRD) in acute myeloid leukemia (AML) in complete remission …
measurable residual disease (MRD) in acute myeloid leukemia (AML) in complete remission …
Treatment of older adults with FLT3-mutated AML: Emerging paradigms and the role of frontline FLT3 inhibitors
NJ Short, D Nguyen, F Ravandi - Blood cancer journal, 2023 - nature.com
FLT3 is the most frequently mutated gene in acute myeloid leukemia (AML), with FLT3
internal tandem duplication (ITD) mutations being associated with a more aggressive clinical …
internal tandem duplication (ITD) mutations being associated with a more aggressive clinical …
Management of acute myeloid leukemia: a review for general practitioners in oncology
RJ Stubbins, A Francis, F Kuchenbauer, D Sanford - Current oncology, 2022 - mdpi.com
Acute myeloid leukemia (AML) is a hematologic malignancy that most frequently develops in
older adults. Overall, AML is associated with a high mortality although advancements in …
older adults. Overall, AML is associated with a high mortality although advancements in …
How I treat AML incorporating the updated classifications and guidelines
F El Chaer, CS Hourigan… - Blood, The Journal of the …, 2023 - ashpublications.org
Abstract The European LeukemiaNet recently revised both the clinical (2022) and
measurable residual disease testing (2021) guidelines for acute myeloid leukemia (AML) …
measurable residual disease testing (2021) guidelines for acute myeloid leukemia (AML) …