[HTML][HTML] Toll-like Receptors as Pro-Thrombotic Drivers in Viral Infections: A Narrative Review

B Panzer, CW Kopp, C Neumayer, R Koppensteiner… - Cells, 2023 - mdpi.com
Toll-like receptors (TLRs) have a critical role in the pathogenesis and disease course of viral
infections. The induced pro-inflammatory responses result in the disturbance of the …

Gut microbiota–derived trimethylamine N-oxide contributes to abdominal aortic aneurysm through inflammatory and apoptotic mechanisms

TW Benson, KA Conrad, XS Li, Z Wang, RN Helsley… - Circulation, 2023 - Am Heart Assoc
Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …

[HTML][HTML] Circular RNAs as a diagnostic and therapeutic target in cardiovascular diseases

VHA Joaquim, NP Pereira, T Fernandes… - International journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a family of noncoding RNAs (ncRNAs) that are endogenous
and widely distributed in different species, performing several functions, mainly their …

[HTML][HTML] Dysregulations of key regulators of angiogenesis and inflammation in abdominal aortic aneurysm

D Zalewski, P Chmiel, P Kołodziej, G Borowski… - International Journal of …, 2023 - mdpi.com
Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …

[HTML][HTML] Bioinformatic analyses of the role of m6A RNA methylation regulators in abdominal aortic aneurysm

C Fu, L Feng, J Zhang, D Sun - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Background N6-methyladenosine (m6A) is found in almost all nuclear RNAs of eukaryotes,
playing an important and diverse role in many biological processes. Nonetheless, the roles …

[HTML][HTML] Association of lipoproteins with neutrophil extracellular traps in patients with abdominal aortic aneurysm

A Brandau, N Ibrahim, J Klopf, H Hayden… - Biomedicines, 2022 - mdpi.com
Neutrophil extracellular traps (NETs) are DNA–protein structures released by neutrophils in
response to various stimuli, including oxidized, low-density lipoprotein (oxLDL) …

The SNP rs4591246 in pri-miR-1-3p is associated with abdominal aortic aneurysm risk by regulating cell phenotypic transformation via the miR-1-3p/TLR4 axis

T Li, J Jing, L Sun, Y Gong, J Yang, C Ma… - International …, 2023 - Elsevier
Emerging evidence reveals that single nucleotide polymorphism (SNP) within miRNAs can
affect the risk of cardiovascular diseases. However, the role of miRNA SNPs in abdominal …

Using machine learning to predict outcomes following suprainguinal bypass

B Li, N Eisenberg, D Beaton, DS Lee, B Aljabri… - Journal of vascular …, 2024 - Elsevier
Objective Suprainguinal bypass for peripheral artery disease (PAD) carries important
surgical risks; however, outcome prediction tools remain limited. We developed machine …

[HTML][HTML] Protection of diabetes in aortic abdominal aneurysm: Are antidiabetics the real effectors?

B Picatoste, I Cerro-Pardo, LM Blanco-Colio… - Frontiers in …, 2023 - frontiersin.org
Aortic aneurysms, including abdominal aortic aneurysms (AAAs), is the second most
prevalent aortic disease and represents an important cause of death worldwide. AAA is a …

Predicting outcomes following endovascular abdominal aortic aneurysm repair using machine learning

B Li, R Verma, D Beaton, H Tamim, MA Hussain… - Annals of …, 2024 - journals.lww.com
Objective: To develop machine learning (ML) models that predict outcomes following
endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA). Background …