[HTML][HTML] Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

L Wang, Y Yan, L Wu, J Peng - Pharmacological Research, 2023 - Elsevier
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …

Epidemiological characteristics and management of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis in China: A narrative review

R Lu, Y Liu, T Hong - Diabetes, Obesity and Metabolism, 2023 - Wiley Online Library
Aim With industrialization and spread of the westernized lifestyle, the number of people
affected by non‐alcoholic fatty liver disease (NAFLD)/non‐alcoholic steatohepatitis (NASH) …

Programmed cell death and lipid metabolism of macrophages in NAFLD

Z Xiao, M Liu, F Yang, G Liu, J Liu, W Zhao… - Frontiers in …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) has now become the leading chronic liver disease
worldwide with lifestyle changes. This may lead to NAFLD becoming the leading cause of …

Machine learning identifies ferroptosis-related gene ANXA2 as potential diagnostic biomarkers for NAFLD

J Qin, P Cao, X Ding, Z Zeng, L Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-alcoholic fatty liver disease (NAFLD), a major cause of chronic liver
disease, still lacks effective therapeutic targets today. Ferroptosis, a type of cell death …

[HTML][HTML] Anti-hyperlipidemic and antioxidant ability of HeShouWu (roots of Polygonum multiflorum Thunb.) and its complex formula

PH Huang, YT Cheng, YJ Chan, SJ Chen… - Arabian Journal of …, 2023 - Elsevier
Many studies have confirmed the effectiveness of herbal medicines or complex formulations
in clinical therapy for metabolic diseases. This study investigated the effects of a HeShouWu …

Nutrition, nutraceuticals and bioactive compounds in the prevention and fight against inflammation

S Surma, A Sahebkar, M Banach - Nutrients, 2023 - mdpi.com
SARS-CoV-2—severe acute respiratory syndrome coronavirus 2; MetS—metabolic
syndrome; DMT2—diabetes mellitus type 2; MAFLD—metabolic-associated fatty liver …

LCN2 contributes to the improvement of nonalcoholic steatohepatitis by 8-Cetylberberine

H He, X Chai, J Li, C Li, X Wu, X Ye, H Ma, X Li - Life Sciences, 2023 - Elsevier
Aims Nonalcoholic steatohepatitis (NASH) is becoming one of the most common causes of
liver transplantation and hepatocellular carcinoma, but no specific drugs are FDA-approved …

Berberine attenuates obesity‐induced insulin resistance by inhibiting miR‐27a secretion

J Du, Y Zhu, X Yang, X Geng, Y Xu, M Zhang… - Diabetic …, 2024 - Wiley Online Library
Introduction Berberine (BBR) is an alkaloid found in plants. It has neuroprotective, anti‐
inflammatory and lipid‐lowering activity. However, the efficacy of treatment with BBR and the …

The Potential of the Nutraceutical Berberine in the Treatment of Hepatocellular Carcinoma and other Liver Diseases such as NAFLD and NASH.

M Cervello, G Augello, L Cocco, S Ratti… - Advances in Biological …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a common cancer which unfortunately has poor
outcomes. Common anti-cancer treatments such as chemotherapy and targeted therapy …

Berberine Protects against Hepatocellular Carcinoma Progression by Regulating Intrahepatic T Cell Heterogeneity

J Hu, Q Shi, C Xue, Q Wang - Advanced Science, 2024 - Wiley Online Library
Accumulating evidence suggests that berberine (BBR) exhibits anti‐cancer effects in
hepatocellular carcinoma (HCC). However, the mechanisms by which BBR regulates the …