Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina
S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …
From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment
A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …
including age-related macular degeneration and diabetic retinopathy, have their origin in the …
Retinal glutamate neurotransmission: from physiology to pathophysiological mechanisms of retinal ganglion cell degeneration
I Boccuni, R Fairless - Life, 2022 - mdpi.com
Glutamate neurotransmission and metabolism are finely modulated by the retinal network,
where the efficient processing of visual information is shaped by the differential distribution …
where the efficient processing of visual information is shaped by the differential distribution …
Microbiome dysbiosis: a pathological mechanism at the intersection of obesity and glaucoma
S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …
individuals have a high risk of developing elevated intraocular pressure and glaucoma …
A review on mesenchymal stem cells for treatment of retinal diseases
S Adak, D Magdalene, S Deshmukh, D Das… - Stem cell reviews and …, 2021 - Springer
Abstract Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment
of several retinal diseases. The therapeutic potential of MSCs lies in its ability to differentiate …
of several retinal diseases. The therapeutic potential of MSCs lies in its ability to differentiate …
Oxidative stress in optic neuropathies
B Sanz-Morello, H Ahmadi, R Vohra, S Saruhanian… - Antioxidants, 2021 - mdpi.com
Increasing evidence indicates that changes in the redox system may contribute to the
pathogenesis of multiple optic neuropathies. Optic neuropathies are characterized by the …
pathogenesis of multiple optic neuropathies. Optic neuropathies are characterized by the …
Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies
NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
The interaction between microglia and macroglia in glaucoma
X Zhao, R Sun, X Luo, F Wang, X Sun - Frontiers in Neuroscience, 2021 - frontiersin.org
Glaucoma, a neurodegenerative disease that leads to irreversible vision loss, is
characterized by progressive loss of retinal ganglion cells (RGCs) and optic axons. To date …
characterized by progressive loss of retinal ganglion cells (RGCs) and optic axons. To date …
The susceptibility of retinal ganglion cells to glutamatergic excitotoxicity is type-specific
I Christensen, B Lu, N Yang, K Huang… - Frontiers in …, 2019 - frontiersin.org
Retinal ganglion cells (RGCs) are the only output neurons that conduct visual signals from
the eyes to the brain. RGC degeneration occurs in many retinal diseases leading to …
the eyes to the brain. RGC degeneration occurs in many retinal diseases leading to …
Treatment of glaucoma with natural products and their mechanism of action: An update
Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by
increased intraocular pressure, which results in damage of the optic nerve and retinal …
increased intraocular pressure, which results in damage of the optic nerve and retinal …