Tumour-associated macrophages (TAMs) are crucial components of the tumour
microenvironment and play a significant role in tumour development and drug resistance by …

Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …

The tumor microenvironment is a dynamic, complex, and redundant network of interactions
between tumor, immune, and stromal cells. In this intricate environment, cells communicate …

Introduction and objective Muscle-invasive urothelial bladder cancer (MIBC) is associated
with limited response rates to systemic therapy, risk of recurrence and death. Tumor …

Macrophages are potent immune effector cells in innate immunity and exert dual-effects in
the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) make up a …

Lactate can play an immunosuppressive role in the tumor microenvironment and promote
tumor development by recruiting and inducing the activity of immunosuppressive cells and …

Multiple sclerosis is a disabling inflammatory disorder of the central nervous system
characterized by demyelination and neurodegeneration. Given that multiple sclerosis …

Single-cell RNA sequencing (scRNA-seq) is an emerging technology used for cellular
transcriptome analysis. The application of scRNA-seq has led to profoundly advanced …