[HTML][HTML] Neuron-astrocyte interactions in Parkinson's disease

I Miyazaki, M Asanuma - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disease. PD
patients exhibit motor symptoms such as akinesia/bradykinesia, tremor, rigidity, and postural …

The role of neurovascular system in neurodegenerative diseases

A Ahmad, V Patel, J Xiao, MM Khan - Molecular neurobiology, 2020 - Springer
The neurovascular system (NVS), which consisted of neurons, glia, and vascular cells, is a
functional and structural unit of the brain. The NVS regulates blood-brain barrier (BBB) …

Glia: a major player in glutamate–GABA dysregulation‐mediated neurodegeneration

A Sood, K Preeti, V Fernandes… - Journal of …, 2021 - Wiley Online Library
The imbalance between glutamate and γ‐aminobutyric acid (GABA) results in the loss of
synaptic strength leading to neurodegeneration. The dogma on the field considered neurons …

[HTML][HTML] Aquaporin-4 polymorphisms are associated with cognitive performance in Parkinson's Disease

Y Fang, S Dai, C Jin, X Si, L Gu, Z Song… - Frontiers in aging …, 2022 - frontiersin.org
Objective Aquaporin-4 (AQP4) facilitates a sleep-enhanced interstitial brain waste clearance
system. This study was conducted to determine the clinical implication of AQP4 …

[HTML][HTML] Ion channel dysfunction in astrocytes in neurodegenerative diseases

S Wang, B Wang, D Shang, K Zhang, X Yan… - Frontiers in …, 2022 - frontiersin.org
Astrocytes play an important role in the central nervous system (CNS). Ion channels in these
cells not only function in ion transport, and maintain water/ion metabolism homeostasis, but …

[HTML][HTML] Aquaporin-4 and cognitive disorders

Y Wang, C Huang, Q Guo, H Chu - Aging and disease, 2022 - ncbi.nlm.nih.gov
Abstract Aquaporin-4 (AQP4) is the most abundantly expressed aquaporin in the central
nervous system (CNS) and is an integral part of the glymphatic system that cannot be …

Nootkatone alleviates rotenone‐induced Parkinson's disease symptoms through activation of the PI3K/Akt signaling pathway

Z Yao, J Li, L Bian, Q Li, X Wang, X Yang… - Phytotherapy …, 2022 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Nootkatone (NKT) has been shown to have neuroprotective, anti‐inflammatory …

[HTML][HTML] Aquaporins in insulin resistance and diabetes: more than channels!

M Galli, A Hameed, A Żbikowski, P Zabielski - Redox biology, 2021 - Elsevier
Aquaporins (AQPs) are part of the family of the integral membrane proteins. Their function is
dedicated to the transport of water, glycerol, ammonia, urea, H 2 O 2, and other small …

[HTML][HTML] Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures

R Dhanwani, JR Lima-Junior, A Sethi, J Pham… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) is a multi-stage neurodegenerative disorder with largely unknown
etiology. Recent findings have identified PD-associated autoimmune features including …

Probiotics and the treatment of Parkinson's disease: An update

H Mirzaei, S Sedighi, E Kouchaki, E Barati… - Cellular and molecular …, 2022 - Springer
Parkinson's disease (PD) is a progressive neurological disorder characterized by motor and
non-motor features. Although some progress has been made in conventional PD treatments …