Saliva is a complex fluid produced by 3 pairs of major salivary glands and by hundreds of
minor salivary glands. It comprises a large variety of constituents and physicochemical …

Purpose Radiation-induced fibrosis (RIF) is a long-term side effect of external beam
radiation therapy for the treatment of cancer. It results in a multitude of symptoms that …

Ionizing radiation is an important treatment modality for a variety of malignant conditions.
However, development of radiation-induced skin changes is a significant adverse effect of …

Purpose: To compare directly the effect of intensity-modulated radiotherapy (IMRT) vs.
conventional radiotherapy (CRT) on salivary flow and quality of life (QoL) in patients with …

PURPOSE: Volumetric intensity-modulated arc therapy (RA) allows for rapid delivery of
highly conformal dose distributions. In this study, planning and dosimetry of RA were …

Background As proton beam radiation therapy (PBRT) may allow greater normal tissue
sparing when compared with intensity-modulated radiation therapy (IMRT), we compared …

Squamous cell carcinoma of the hypopharynx represents a distinct clinical entity. Most
patients present with significant comorbidities and advanced‐stage disease. The overall …

PURPOSE: The purpose of this study was to compare intensity-modulated radiation therapy
(IMRT) and three-dimensional conventional radiotherapy (3D-CRT) with regard to patient …

Purpose: We investigated the factors that affect salivary function after head-and-neck
radiotherapy (RT), including parotid gland dose-volume effects, potential compensation by …

Over the past 10 years, quality of life (QOL) has been increasingly recognised as an
important outcome parameter in head and neck cancer. Validated questionnaires have …