Abstract Study Objectives: To evaluate safety and efficacy of phentermine 15 mg plus
extended-release topiramate 92 mg for treatment of moderate to severe obstructive sleep …

Introduction: Weight-management options include lifestyle modifications, bariatric surgery
and, until recently, limited pharmacotherapy. Phentermine and topiramate extended-release …

We aimed to evaluate existing research into the effectiveness and safety of two tongue base
suspension (TBS) techniques (Repose® system and modified TBS) with or without …

Increased loop gain (a function of both controller gain and plant gain), which results in
instability in feedback control, is of major importance in producing recurrent central apnoeas …

Objectives: For the first time ever, as emphasized by inclusion in the Healthy People 2020
goals, sleep health is an emphasis of national health aims. The National Healthy Sleep …

The aim of this study was to evaluate the effects of modified tongue base suspension
(mTBS) procedure on continuous positive airway pressure (CPAP) levels in patients with …

Background/aim: The aim of this study was to investigate alterations in voice parameters
among patients using continuous positive airway pressure (CPAP) for the treatment of …

Despite many advances in the treatment of obstructive sleep apnea with CPAP therapy,
adherence remains poor in many patients. To optimize the treatment of OSA, it is crucial to …

Obstructive sleep apnoea, OSA, is formally defined as an apnoeahypopnoea index (AHI) of
at least 5 episodes/hour (mild). Obesity, alcohol, smoking and sedatives may contribute to …

Objectives Inflammation of the upper airways, thickening of the lateral pharyngeal walls,
elongation of the soft palate and uvula, hypertrophy of the tonsils and base of the tongue can …