[HTML][HTML] Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities

J Li, Z Ming, L Yang, T Wang, G Liu, Q Ma - Genes & Diseases, 2022 - Elsevier
Sexual dimorphism has been reported in various human diseases including autoimmune
diseases, neurological diseases, pulmonary arterial hypertension, and some types of …

Epigenetic modification and BRAF gene mutation in thyroid carcinoma

G Huang, J Chen, J Zhou, S Xiao, W Zeng, J Xia… - Cancer Cell …, 2021 - Springer
Thyroid cancer remains the most prevailing endocrine malignancy, and a progressively
increasing incidence rate has been observed in recent years, with 95% of thyroid cancer …

The talented LncRNAs: meshing into transcriptional regulatory networks in cancer

D Segal, J Dostie - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) are a large class of RNA molecules
known to regulate the expression of genes. Although expressed in a highly tissue-specific …

Analysis of SNHG14: A Long Non-Coding RNA Hosting SNORD116, Whose Loss Contributes to Prader–Willi Syndrome Etiology

S Ariyanfar, DJ Good - Genes, 2022 - mdpi.com
The Small Nucleolar Host Gene 14 (SNHG14) is a host gene for small non-coding RNAs,
including the SNORD116 small nucleolar C/D box RNA encoding locus. Large deletions of …

An unanticipated modulation of cyclin-dependent kinase inhibitors: the role of long non-coding RNAs

D Bencivenga, E Stampone, A Vastante, M Barahmeh… - Cells, 2022 - mdpi.com
It is now definitively established that a large part of the human genome is transcribed.
However, only a scarce percentage of the transcriptome (about 1.2%) consists of RNAs that …

Assisted reproductive technology and imprinting errors: analyzing underlying mechanisms from epigenetic regulation

G Zhang, Y Mao, Y Zhang, H Huang, J Pan - Human Fertility, 2023 - Taylor & Francis
With the increasing maturity and widespread application of assisted reproductive technology
(ART), more attention has been paid to the health outcomes of offspring following ART. It is …

Possible role of lncRNAs in amelioration of Parkinson's disease symptoms by transplantation of dopaminergic cells

A Amini, F Esmaeili, M Golpich - npj Parkinson's Disease, 2024 - nature.com
Long non-coding RNAs (lncRNAs) are biomarkers for diagnosis and treatment of
Parkinson's disease (PD). Since dopaminergic cell transplantation is a clinical method to …

[HTML][HTML] Emerging concepts involving inhibitory and activating RNA functionalization towards the understanding of microcephaly phenotypes and brain diseases in …

M Tokunaga, T Imamura - Frontiers in Cell and Developmental …, 2023 - ncbi.nlm.nih.gov
Microcephaly is characterized as a small head circumference, and is often accompanied by
developmental disorders. Several candidate risk genes for this disease have been …

Expression analysis of box C/D snoRNAs with SNPs between C57BL/6 and MSM/Ms strains in male mouse

R Saito, M Otsu, H Kiyosawa, G Kawai - Plos one, 2023 - journals.plos.org
MSM/Ms mouse derived from the Japanese wild mouse has unique characteristics
compared to the widely used C57BL/6 mouse. To examine the usefulness of the MSM/Ms …

Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression

F Zhao, S Li, J Liu, J Wang, B Yang - Human Cell, 2022 - Springer
Diffuse large B cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma (NHL)
globally, featuring heterogeneous clinical phenotypes and altered molecular manifestations …