Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Various whole cell-based biosensors have been reported in the literature for the last 20
years and these reports have shown great potential for their use in the areas of pollution …

Systems biology and synthetic biology are increasingly used to examine and modulate
complex biological systems. As such, many issues arising during scaling-up microbial …

Cell‐based biosensors offer cheap, portable and simple methods of detecting molecules of
interest but have yet to be truly adopted commercially. Issues with their performance and …

Quantification and regulation of pathway metabolites is crucial for optimization of microbial
production bioprocesses. Genetically encoded biosensors provide the means to couple …

Monitoring cellular behavior and eventually properly adapting cellular processes is key to
handle the enormous complexity of today's metabolic engineering questions. Hence …

Aims The purpose of this study was to elucidate the characteristics of multiple alkane
hydroxylase systems in Pseudomonas aeruginosa DN1, including two homologues of AlkB …

The biosynthesis of short-chain alcohols is a carbon-neutral alternative to petroleum-derived
production, but strain screening operations are encumbered by laborious analytics. Here …

Synthetic biology is the repurposing of biological systems for novel objectives and
applications. Through the co-ordinated and balanced expression of genes, both native and …

Novel hydrolases from hot and other extreme environments showing appropriate
performance and/or novel functionalities and new approaches for their systematic screening …