FDA approval summary: palbociclib for male patients with metastatic breast cancer
S Wedam, L Fashoyin-Aje, E Bloomquist, S Tang… - Clinical Cancer …, 2020 - AACR
Abstract On April 4, 2019, the FDA approved a supplemental new drug application for
palbociclib (IBRANCE), to expand the approved indications in women with hormone …
palbociclib (IBRANCE), to expand the approved indications in women with hormone …
Real‐world progression, treatment, and survival outcomes during rapid adoption of immunotherapy for advanced non–small cell lung cancer
Background Despite the rapid adoption of immunotherapies in advanced non–small cell
lung cancer (advNSCLC), knowledge gaps remain about their real‐world (rw) performance …
lung cancer (advNSCLC), knowledge gaps remain about their real‐world (rw) performance …
[HTML][HTML] Generating real-world tumor burden endpoints from electronic health record data: comparison of RECIST, radiology-anchored, and clinician-anchored …
SD Griffith, M Tucker, B Bowser, G Calkins, C Chang… - Advances in …, 2019 - Springer
Introduction Real-world evidence derived from electronic health records (EHRs) is
increasingly recognized as a supplement to evidence generated from traditional clinical …
increasingly recognized as a supplement to evidence generated from traditional clinical …
Characterizing the feasibility and performance of real-world tumor progression end points and their association with overall survival in a large advanced non–small …
SD Griffith, RA Miksad, G Calkins, P You… - JCO clinical cancer …, 2019 - ascopubs.org
PURPOSE Large, generalizable real-world data can enhance traditional clinical trial results.
The current study evaluates reliability, clinical relevance, and large-scale feasibility for a …
The current study evaluates reliability, clinical relevance, and large-scale feasibility for a …
Uptake and survival outcomes following immune checkpoint inhibitor therapy among trial-ineligible patients with advanced solid cancers
Importance Immune checkpoint inhibitors (ICIs) are part of standard of care for patients with
many advanced solid tumors. Patients with poor performance status or organ dysfunction …
many advanced solid tumors. Patients with poor performance status or organ dysfunction …
Moving beyond static survivorship care plans: A systems engineering approach to population health management for cancer survivors
AJ Tevaarwerk, JR Klemp, GJ van Londen, BW Hesse… - Cancer, 2018 - Wiley Online Library
The American cancer survivor population is ever‐growing, with necessary follow‐up
primarily accomplished in a high‐touch fashion—adding to unsustainability and …
primarily accomplished in a high‐touch fashion—adding to unsustainability and …
[HTML][HTML] Immunotherapy treatment patterns and outcomes among ALK-positive patients with non–small-cell lung cancer
M Jahanzeb, HM Lin, X Pan, Y Yin, P Baumann… - Clinical lung cancer, 2021 - Elsevier
Introduction The treatment landscape for anaplastic lymphoma kinase (ALK)-positive non–
small-cell lung cancer (NSCLC) primarily involves ALK-directed tyrosine kinase inhibitors …
small-cell lung cancer (NSCLC) primarily involves ALK-directed tyrosine kinase inhibitors …
Effectiveness of first-line immune checkpoint blockade versus carboplatin-based chemotherapy for metastatic urothelial cancer
Background Limited data compare first-line carboplatin-based chemotherapy and immune
checkpoint blockade in cisplatin-ineligible metastatic urothelial carcinoma (mUC) patients …
checkpoint blockade in cisplatin-ineligible metastatic urothelial carcinoma (mUC) patients …
Treatment patterns and overall survival in metastatic urothelial carcinoma in a real-world, US setting
JC Simeone, BL Nordstrom, K Patel, H Mann… - Cancer …, 2019 - Elsevier
Background Metastatic urothelial carcinoma (mUC) treated with chemotherapy is associated
with poor survival; however, as the field of immuno-oncology continues to evolve, new …
with poor survival; however, as the field of immuno-oncology continues to evolve, new …
[HTML][HTML] Estimating redundancy in clinical text
The current mode of use of Electronic Health Records (EHR) elicits text redundancy.
Clinicians often populate new documents by duplicating existing notes, then updating …
Clinicians often populate new documents by duplicating existing notes, then updating …