The histone methyltransferase SETDB2 modulates tissue inhibitors of metalloproteinase–matrix metalloproteinase activity during abdominal aortic aneurysm …

FM Davis, WJ Melvin, K Mangum, LC Tsoi… - Annals of …, 2023 - journals.lww.com
Objective: To determine macrophage-specific alterations in epigenetic enzyme function
contributing to the development of abdominal aortic aneurysms (AAAs). Background: AAA is …

[HTML][HTML] Angiogenesis in Aortic Aneurysm and Dissection: A Literature Review

Y Jia, D Li, J Yu, W Jiang, Y Liu, F Li, R Zeng… - Reviews in …, 2023 - imrpress.com
Aortic aneurysm and aortic dissection (AA/AD) are critical aortic diseases with a hidden
onset and sudden rupture, usually resulting in an inevitable death. Several pro-and anti …

[HTML][HTML] Pharmacological inhibition of gasdermin d suppresses angiotensin ii-induced experimental abdominal aortic aneurysms

J Guo, J Shi, M Qin, Y Wang, Z Li, T Shoji, T Ikezoe… - Biomolecules, 2023 - mdpi.com
Background: Gasdermin D, a molecule downstream of the nucleotide-binding
oligomerization domain-like receptor family pyrin domain containing inflammasome, forms …

[HTML][HTML] Gasdermin D Inhibitor Necrosulfonamide Alleviates Angiotensin II-Induced Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice

J Guo, Q Zhang, Z Li, M Qin, J Shi, Y Wang, W Ai, J Ju… - Biomolecules, 2024 - mdpi.com
Abdominal aortic aneurysm (AAA) is a chronic aortic disease that lacks effective
pharmacological therapies. This study was performed to determine the influence of …

The incidence rate and histological characteristics of intimal hyperplasia in elastase‐induced experimental abdominal aortic aneurysms in mice

M Li, P Wei, K Li, H Liu, N Alam, H Hou… - Animal Models and …, 2023 - Wiley Online Library
Intimal hyperplasia (IH) is a negative vascular remodeling after arterial injury. IH
occasionally occurs in elastase‐induced abdominal aortic aneurysm (AAA) mouse models …

The Histone Methyltransferase Setdb2 Modulates TIMP-MMP Activity During Abdominal Aortic Aneurysm Development

FM Davis, WJ Melvin, K Mangum, LC Tsoi… - Annals of …, 2023 - journals.lww.com
Objective: To determine macrophage-specific alterations in epigenetic enzyme function
contributing to development of abdominal aortic aneurysms (AAAs). Summary Background …

Cellular Mechanism of Pentagalloyl Gucose-Mediated Prevention and Reversal of Abdominal Aortic Aneurysms

G Halsey - 2023 - search.proquest.com
Abdominal aortic aneurysm (AAA) has been the 15th leading cause of death in persons
older than 55 for the past ten years in several Western countries, with rupture resulting in an …