Combination therapies with EHMT2 inhibitors
JE Campbell, KW Duncan, MA Raimondi… - US Patent …, 2023 - Google Patents
2020-01-14 Assigned to Epizyme, Inc. reassignment Epizyme, Inc. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PENEBRE, Elayne …
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PENEBRE, Elayne …
Substituted pyridine spleen tyrosine kinase (SYK) inhibitors
AM Haidle, SL Knowles, SD Kattar… - US Patent …, 2016 - Google Patents
2015-11-06 Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Substituted diazine and triazine spleen tyrosine kinease (Syk) inhibitors
AM Haidle, MD Altman, SD Kattar… - US Patent …, 2016 - Google Patents
The invention provides certain substituted diazine and triaz ine compounds of the Formula
(I)(I) or pharmaceutically acceptable salts thereof, wherein R', RRRRC, and t are as defined …
(I)(I) or pharmaceutically acceptable salts thereof, wherein R', RRRRC, and t are as defined …
Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors
AM Haidle, J Burch, D Guay, JY Gauthier… - US Patent …, 2016 - Google Patents
The invention provides certain Substituted phenyl compounds of the Formula (I) or
pharmaceutically acceptable salts thereof, wherein R', RRRR, and t are as defined herein …
pharmaceutically acceptable salts thereof, wherein R', RRRR, and t are as defined herein …
Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors
KL Arrington, B DuBois, JS Debenham, P Liu… - US Patent …, 2016 - Google Patents
9,006,444 B2 4/2015 Altman et al. WO 2007042298 A1 4, 2007 9,120,785 B2 9/2015 Altman
et al. WO 2007042.299 A1 4, 2007 9,145,391 B2 9/2015 Deschenes et al. WO 2007070872 …
et al. WO 2007042.299 A1 4, 2007 9,145,391 B2 9/2015 Deschenes et al. WO 2007070872 …
Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors
MR Machacek - US Patent 9,624,210, 2017 - Google Patents
The invention provides certain amino-pyrimidine-contain ing compounds. The invention also
provides pharmaceutical compositions comprising such compounds, and methods of using …
provides pharmaceutical compositions comprising such compounds, and methods of using …
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
MR Machacek, ET Romeo, AB Northrup… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amino heteroaryl compounds of the
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein R', R", RS, RC, A, Cy and …
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein R', R", RS, RC, A, Cy and …
Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors
TA Miller, A Petrocchi, ET Romeo, D Vitharana… - US Patent …, 2017 - Google Patents
US9670196B2 - Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase
inhibitors - Google Patents US9670196B2 - Thiazole-substituted aminoheteroaryls as …
inhibitors - Google Patents US9670196B2 - Thiazole-substituted aminoheteroaryls as …
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
NJ Anthony, BM Andresen, AB Northrup… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amino heteroaryl compounds of the
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein X, X2, X3, X4, Y', Y?, Y> …
Formula (I) or pharmaceuti cally acceptable salts thereof, wherein X, X2, X3, X4, Y', Y?, Y> …
Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors
MD Altman, BM Andresen, KL Arrington… - US Patent …, 2017 - Google Patents
The invention provides certain thiazole-substituted amin opyridine compounds of the
Formula (I)(I) or pharmaceu tically acceptable salts thereof, wherein RRRRR RC, and the …
Formula (I)(I) or pharmaceu tically acceptable salts thereof, wherein RRRRR RC, and the …