In the present world scenario, obesity has almost attained the level of a pandemic and is
progressing at a rapid rate. This disease is the mother of all other metabolic disorders, which …

Cellular energy is primarily provided by the oxidative degradation of nutrients coupled with
mitochondrial respiration, in which oxygen participates in the mitochondrial electron …

Protein-ligand docking simulation is central in drug design and development. Therefore, the
development of web servers intended to docking simulations is of pivotal importance …

AMP-activated protein kinase (AMPK) is an evolutionary conserved and ubiquitously
expressed serine/threonine kinase playing a central role in the coordination of energy …

AMP-activated protein kinase (AMPK) is a crucial metabolic regulator with profound
modulatory activities on inflammation. Although the anti-inflammatory benefits of AMPK …

Docking calculations can accelerate drug discovery by predicting the bound poses of
ligands for a targeted protein. However, it is not clear which docking methods work best …

Dietary phenolic compounds are considered as bioactive compounds that have effects in
different chronic disorders related to oxidative stress, inflammation process, or aging. These …

Nonalcoholic fatty liver disease (NAFLD) is a worldwide public health issue, but a widely
accepted therapy is still lacking until now. Anthocyanins are natural flavonoid compounds …

The 5′-adenosine monophosphate-activated protein kinase (AMPK) is an important
metabolic regulator. Its allosteric drug and metabolite binding (ADaM) site was identified as …

AMP-activated protein kinase (AMPK) plays a major role in maintaining cellular energy
homeostasis by sensing and responding to AMP/ADP concentrations relative to ATP. AMPK …