Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis

MA Holden, M Hattle, J Runhaar, RD Riley… - The Lancet …, 2023 - thelancet.com
Background Many international clinical guidelines recommend therapeutic exercise as a
core treatment for knee and hip osteoarthritis. We aimed to identify individual patient-level …

Evidence-Based Dietary Practices to Improve Osteoarthritis Symptoms: An Umbrella Review

AN Buck, HK Vincent, CB Newman, JA Batsis… - Nutrients, 2023 - mdpi.com
While there is some research investigating whole foods or diets that are easily understood
and accessible to patients with osteoarthritis, specific nutrients or nutraceuticals are more …

Glucagon-like peptide-1 receptor agonists as a disease-modifying therapy for knee osteoarthritis mediated by weight loss: findings from the Shanghai Osteoarthritis …

H Zhu, L Zhou, Q Wang, Q Cai, F Yang, H Jin… - Annals of the …, 2023 - ard.bmj.com
Objective Obesity is a risk factor for knee osteoarthritis (KOA) development and progression.
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are indicated for type 2 diabetes …

Epigenetics in Knee Osteoarthritis: A 2020–2023 Update Systematic Review

D Caldo, E Massarini, M Rucci, S Deaglio, R Ferracini - Life, 2024 - mdpi.com
Osteoarthritis is a leading cause of disability in the world. The scientific literature highlights
the critical importance of epigenetic regulatory effects, intertwined with biomechanical and …

Osteoarthritis year in review 2023: Epidemiology & therapy

AV Perruccio, JJ Young, JM Wilfong, JD Power… - Osteoarthritis and …, 2023 - Elsevier
Objective To highlight some important findings from osteoarthritis (OA) epidemiology and
therapy research undertaken over the past year. Methods Search of MEDLINE and EMBASE …

The emperor's new clothes?

M Englund, A Turkiewicz - Osteoarthritis and Cartilage, 2023 - oarsijournal.com
Background The 'Emperor's New Clothes' is a classic Danish tale written by Hans Christian
Andersen. The story has been translated into over 100 languages. In brief, the plot is about a …

[HTML][HTML] The osteoarthritis prevention study (TOPS)-A randomized controlled trial of diet and exercise to prevent Knee Osteoarthritis: Design and rationale

SP Messier, LF Callahan, E Losina, SL Mihalko… - … and Cartilage Open, 2024 - Elsevier
Background Osteoarthritis (OA), the leading cause of disability among adults, has no cure
and is associated with significant comorbidities. The premise of this randomized clinical trial …

Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysis

X Lv, F Liang, S Liu, X Deng, R Lai, J Du, J Luo - Plos one, 2024 - journals.plos.org
Background Knee osteoarthritis (KOA) is a common disabling joint disease that affects
millions of people worldwide. Diet may play a role in the etiology and progression of KOA …

[HTML][HTML] OARSI year in review 2023: Rehabilitation and outcomes

EM Macri, RW Selles, JJ Stefanik, M Reijman - Osteoarthritis and Cartilage, 2023 - Elsevier
Objective We systematically reviewed the literature to identify comparative studies of core
treatments (exercise, education, or weight management), adjunct treatments (eg …

Integrated analysis of transcriptome changes in osteoarthritis: gene expression, pathways and alternative splicing

C Li, P Wei, L Wang, Q Wang, H Wang, Y Zhang - Cartilage, 2023 - journals.sagepub.com
Objective Osteoarthritis (OA) is the most prevalent joint disease characterized by the
degeneration of articular cartilage and the remodeling of its underlying bones, resulting in …