Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society

MT Mackay, SK Weiss, T Adams-Webber, S Ashwal… - Neurology, 2004 - AAN Enterprises
Objective: To determine the current best practice for treatment of infantile spasms in children.
Methods: Database searches of MEDLINE from 1966 and EMBASE from 1980 and searches …

Metabolic etiologies in West syndrome

S Salar, SL Moshé, AS Galanopoulou - Epilepsia Open, 2018 - Wiley Online Library
West syndrome (WS) is an early life epileptic encephalopathy associated with infantile
spasms, interictal electroencephalography (EEG) abnormalities including high amplitude …

Pyridoxal phosphate is better than pyridoxine for controlling idiopathic intractable epilepsy

HS Wang, MF Kuo, ML Chou, PC Hung… - Archives of disease in …, 2005 - adc.bmj.com
Aim: To study the difference between pyridoxine (PN) and its active form, pyridoxal
phosphate,(PLP) in control of idiopathic intractable epilepsy in children. Methods: Among …

Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin: a 12-month assessment of spasm control in West …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2017 - Elsevier
Objective We earlier completed a single-blind, parallel-group, randomized clinical trial to test
the null hypothesis that adrenocorticotropic hormone (ACTH) is not superior to high-dose …

Low-dose ACTH therapy for West syndrome: initial effects and long-term outcome

M Ito, H Aiba, K Hashimoto, S Kuroki, K Tomiwa… - Neurology, 2002 - AAN Enterprises
Background: Most Japanese pediatric neurologists attempt other treatments before using
adrenocorticotropic hormone (ACTH) therapy for West syndrome (WS), and even then, they …

Adrenocorticotropic hormone versus pulsatile dexamethasone in the treatment of infantile epilepsy syndromes

E Haberlandt, C Weger, SB Sigl, M Rauchenzauner… - Pediatric …, 2010 - Elsevier
For treatment of intractable epilepsies, there are no data comparing conventional
adrenocorticotropic hormone and pulsatile corticoid therapy with dexamethasone. A …

Altered hippocampal kynurenine pathway metabolism contributes to hyperexcitability in human mesial temporal lobe epilepsy–hippocampal sclerosis

S Dey, A Banerjee Dixit, M Tripathi… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Glutamate receptor‐mediated enhanced excitatory
neurotransmission is typically associated with mesial temporal lobe epilepsy with …

Current trends in the treatment of infantile spasms

CY Tsao - Neuropsychiatric disease and treatment, 2009 - Taylor & Francis
Infantile spasms are an epilepsy syndrome with distinctive features, including age onset
during infancy, characteristic epileptic spasms, and specific electroencephalographic …

[HTML][HTML] PNPO deficiency

B Plecko, P Mills - 2022 - europepmc.org
PNPO Deficiency - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
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Extremely low-dose ACTH step-up protocol for West syndrome: maximum therapeutic effect with minimal side effects

H Oguni, S Yanagaki, K Hayashi, K Imai… - Brain and …, 2006 - Elsevier
We studied the effectiveness of our new ACTH treatment strategy for West syndrome (WS),
which was based on the results of our previous extremely low-dose ACTH study. The …