Antioxidative and anti-inflammatory properties of cannabidiol

S Atalay, I Jarocka-Karpowicz, E Skrzydlewska - Antioxidants, 2019 - mdpi.com
Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …

Food as medicine: targeting the uraemic phenotype in chronic kidney disease

D Mafra, NA Borges, B Lindholm, PG Shiels… - Nature Reviews …, 2021 - nature.com
The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

Broccoli or sulforaphane: is it the source or dose that matters?

Y Yagishita, JW Fahey, AT Dinkova-Kostova… - Molecules, 2019 - mdpi.com
There is robust epidemiological evidence for the beneficial effects of broccoli consumption
on health, many of them clearly mediated by the isothiocyanate sulforaphane. Present in the …

Anticancer therapy with HDAC inhibitors: mechanism-based combination strategies and future perspectives

R Jenke, N Reßing, FK Hansen, A Aigner, T Büch - Cancers, 2021 - mdpi.com
Simple Summary Beyond mutations, epigenetic changes have been described as drivers for
cancer as well. While leaving the overall DNA structure intact, they can be responsible for …

[HTML][HTML] Knowledge domain and emerging trends in ferroptosis research: a bibliometric and knowledge-map analysis

J Zhang, L Song, L Xu, Y Fan, T Wang, W Tian… - Frontiers in …, 2021 - frontiersin.org
Objectives To identify the cooperation and impact of authors, countries, institutions, and
journals, evaluate the knowledge base, find the hotspot trends, and detect the emerging …

Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

Natural products as modulators of Nrf2 signaling pathway in neuroprotection

I Moratilla-Rivera, M Sánchez… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …

[HTML][HTML] Knowledge mapping of necroptosis from 2012 to 2021: a bibliometric analysis

J Zhang, L Song, J Jia, W Tian, R Lai, Z Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Necroptosis, a recently discovered programmed cell death, has been
pathologically linked to various diseases and is thus a promising target for treating diseases …

Research trends, hot spots and prospects for necroptosis in the field of neuroscience

WT Yan, S Lu, YD Yang, WY Ning, Y Cai… - Neural regeneration …, 2021 - journals.lww.com
There are two types of cell death-apoptosis and necrosis. Apoptosis is cell death regulated
by cell signaling pathways, while necrosis has until recently been considered a passive …

[HTML][HTML] Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer

M Fallah, A Davoodvandi, S Nikmanzar, S Aghili… - Biomedicine & …, 2021 - Elsevier
Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …