[HTML][HTML] Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer
M Fallah, A Davoodvandi, S Nikmanzar, S Aghili… - Biomedicine & …, 2021 - Elsevier
Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …
The role of natural products in revealing NRF2 function
Covering: up to 2020 The transcription factor NRF2 is one of the body's major defense
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …
mechanisms, driving transcription of> 300 antioxidant response element (ARE)-regulated …
[HTML][HTML] Current landscape of NRF2 biomarkers in clinical trials
Y Yagishita, TN Gatbonton-Schwager, ML McCallum… - Antioxidants, 2020 - mdpi.com
The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) plays a
critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the …
critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the …
A molecular basis for the anti‐inflammatory and anti‐fibrosis properties of cannabidiol
Cannabidiol (CBD) is considered a non‐psychoactive, antioxidant, and anti‐inflammatory
compound derived from the Cannabis sativa plant. There are various reports on the versatile …
compound derived from the Cannabis sativa plant. There are various reports on the versatile …
[HTML][HTML] Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an essential transcription factor that
maintains the cell's redox balance state and reduces inflammation in different adverse …
maintains the cell's redox balance state and reduces inflammation in different adverse …
[HTML][HTML] Molecular iodine has extrathyroidal effects as an antioxidant, differentiator, and immunomodulator
Most investigations of iodine metabolism in humans and animals have focused on its role in
thyroid function. However, considerable evidence indicates that iodine could also be …
thyroid function. However, considerable evidence indicates that iodine could also be …
[HTML][HTML] Sulforaphane protects cells against lipopolysaccharide-stimulated inflammation in murine macrophages
Inflammation is an essential part for the general or innate immune defenses to defend
against tissue damage and accelerate the curing process by providing protection against …
against tissue damage and accelerate the curing process by providing protection against …
[HTML][HTML] Cannabidiol: bridge between antioxidant effect, cellular protection, and cognitive and physical performance
G Jîtcă, BE Ősz, CE Vari, CM Rusz, A Tero-Vescan… - Antioxidants, 2023 - mdpi.com
The literature provides scientific evidence for the beneficial effects of cannabidiol (CBD), and
these effects extend beyond epilepsy treatment (eg, Lennox–Gastaut and Dravet …
these effects extend beyond epilepsy treatment (eg, Lennox–Gastaut and Dravet …
Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease
LFMF Cardozo, LA Alvarenga, M Ribeiro, L Dai… - Nutrition …, 2021 - academic.oup.com
Sulforaphane (SFN) is a sulfur-containing isothiocyanate found in cruciferous vegetables
(Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 …
(Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 …
Dual and opposite roles of reactive oxygen species (ROS) in Chagas disease: beneficial on the pathogen and harmful on the host
Chagas disease is a neglected tropical disease, which affects an estimate of 6‐7 million
people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic …
people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic …