Astrocytes are abundant glial cells in the central nervous system (CNS) that control multiple
aspects of health and disease. Through their interactions with components of the blood …

Inflammation is a biological process that dynamically alters the surrounding
microenvironment, including participating immune cells. As a well‐protected organ …

Microglia are highly plastic immune cells which exist in a continuum of activation states. By
shaping the function of oligodendrocyte precursor cells (OPCs), the brain cells which …

The cross-talk between T cells and astrocytes occurring under physiological and, even
more, neuroinflammatory conditions may profoundly impact the generation of adaptive …

Multiple sclerosis (MS) is a highly disabling, progressive neurodegenerative disease with no
curative treatment available. Although significant progress has been made in understanding …

Reactive astrocytes are a hallmark of neurodegenerative disease including multiple
sclerosis. It is widely accepted that astrocytes may adopt alternative phenotypes depending …

Extracellular vesicles (EVs) are involved in the regulation of immune system functioning and
central nervous system (CNS) homeostasis, suggesting a possible role in multiple sclerosis …

Transposable elements (TEs) are crucial for genetic diversity and gene regulation. Current
single-cell quantification methods often align multi-mapping reads to eitherbest …

Molecular adaptors are proteins implicated in the regulation of the cellular responses to
environmental stimuli, which can be involved in different signaling pathways depending on …

In the recent years, extracellular vesicles (EVs) drew a growing interest in scientific
community, especially for their intrinsic role of cell-cell communication entities between local …