Biomolecular condensates are found throughout eukaryotic cells, including in the nucleus, in
the cytoplasm and on membranes. They are also implicated in a wide range of cellular …

Organ development and homeostasis involve dynamic interactions between individual cells
that collectively regulate tissue architecture and function. To ensure the highest tissue …

Even among genetically identical cancer cells, resistance to therapy frequently emerges
from a small subset of those cells,,,,,–. Molecular differences in rare individual cells in the …

Background Heterogeneity in single-cell RNA-seq (scRNA-seq) data is driven by multiple
sources, including biological variation in cellular state as well as technical variation …

Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several
states across the epithelial–mesenchymal landscape, thereby acquiring hybrid epithelial …

Thermodynamics serves as a universal means for studying physical systems from an energy
perspective. In recent years, with the establishment of the field of stochastic and quantum …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease with no effective
treatments. Due to cellular heterogeneity, defining the roles of immune cell subsets in AD …

Phase-separated multi-molecular assemblies provide a general regulatory mechanism to
compartmentalize biochemical reactions within cells. We propose that a phase separation …

Cellular processes are carried out by many genes, and their study and optimization requires
multiple levers by which they can be independently controlled. The most common method is …

Spontaneous deracemizations is a challenging, multidisciplinary subject in current chirality
research. In the absence of any chiral inductors, an achiral substance or a racemic …