[HTML][HTML] Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions

A Radaic, YL Kapila - Computational and structural biotechnology journal, 2021 - Elsevier
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …

[HTML][HTML] Microbial etiology and prevention of dental caries: exploiting natural products to inhibit cariogenic biofilms

X Chen, EBM Daliri, N Kim, JR Kim, D Yoo, DH Oh - Pathogens, 2020 - mdpi.com
Dental caries is one of the most common microbe-mediated oral diseases in human beings.
At present, the accepted etiology of caries is based on a four-factor theory that includes oral …

Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

[HTML][HTML] Biofilms: Formation, drug resistance and alternatives to conventional approaches

R Mirghani, T Saba, H Khaliq, J Mitchell, L Do… - AIMS …, 2022 - ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …

Inhibition of Streptococcus mutans biofilm formation by strategies targeting the metabolism of exopolysaccharides

Y Lin, J Chen, X Zhou, Y Li - Critical Reviews in Microbiology, 2021 - Taylor & Francis
Dental caries is one of the most prevalent and costly biofilm-associated infectious diseases
affecting most of the world's population. In particular, dental caries is driven by dysbiosis of …

[HTML][HTML] Promising therapeutic strategies against microbial biofilm challenges

K Zhang, X Li, C Yu, Y Wang - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Biofilms are communities of microorganisms that are attached to a biological or abiotic
surface and are surrounded by a self-produced extracellular matrix. Cells within a biofilm …

[HTML][HTML] Nanotechnology in combating biofilm: A smart and promising therapeutic strategy

YK Mohanta, I Chakrabartty, AK Mishra… - Frontiers in …, 2023 - frontiersin.org
Since the birth of civilization, people have recognized that infectious microbes cause serious
and often fatal diseases in humans. One of the most dangerous characteristics of …

New strategies and mechanisms for targeting Streptococcus mutans biofilm formation to prevent dental caries: a review

Z Gao, X Chen, C Wang, J Song, J Xu, X Liu… - Microbiological …, 2023 - Elsevier
Dental caries, a prevalent oral infectious disease, is intricately linked to the biofilm formation
on the tooth surfaces by oral microbes. Among these, Streptococcus mutans plays a central …

N-Terminal Lysozyme Conjugation to a Cationic Polymer Enhances Antimicrobial Activity and Overcomes Antimicrobial Resistance

T Zhang, W An, J Sun, F Duan, Z Shao, F Zhang… - Nano Letters, 2022 - ACS Publications
Microbial resistance to antibiotics is one of the greatest global healthcare challenges. There
is an urgent need to develop effective strategies to overcome antimicrobial resistance. We …