Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …

The liver is an organ that performs a multitude of functions, and its health is pertinent and
indispensable to survival. Thus, the cellular and molecular machinery driving hepatic …

Liver zonation, the spatial separation of the immense spectrum of different metabolic
pathways along the liver sinusoids, is fundamental for proper functioning of this organ …

Pre-B-cell colony enhancing factor (PBEF) was first isolated from an activated peripheral
blood lymphocyte cDNA library and was found to be involved in the maturation of B-cell …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. Although recent advances in therapeutic approaches for treating HCC have …

Quiescent hepatic stellate cells (HSCs), in response to liver injury, undergo characteristic
morphological transformation into proliferative, contractile and ECM-producing …

Alzheimer's disease (AD) is the most common cause of dementia, affecting more than 36
million people worldwide. AD is characterized by a progressive loss of cognitive functions …

Systemic sclerosis (SSc) is an autoimmune disease characterized by extensive visceral
organ and skin fibrosis. SSc patients have increased production of autoreactive antibodies …

The ghrelin gene peptides include acylated ghrelin (AG), unacylated ghrelin (UAG), and
obestatin (Ob). AG, mainly produced by the stomach, exerts its central and peripheral effects …

Glypican 3 (GPC3) is a heparan sulfate proteoglycan and cell surface oncofetal protein
which is highly expressed on a variety of pediatric solid embryonal tumors including the …