Inorganic arsenic (iAs) is a complete transplacental carcinogen in mice. Previous studies
have demonstrated that in utero exposure to iAs promotes cancer in adult mouse offspring …

Abstract Transcription factor 1 (Tcf1; hepatocyte nuclear factor 1α [HNF1α]) is critical for
hepatocyte development and function. Whether Tcf1 also regulates hepatic microRNAs …

The roof plate-specific spondin–leucine-rich repeat-containing G-protein coupled receptor
4/5 (LGR4/5)–zinc and ring finger 3 (ZNRF3)/ring finger protein 43 (RNF43) module is a …

Pregnancy is characterized by physiological adjustments in the maternal compartment. In
this investigation, the influence of pregnancy on maternal liver was examined in CD-1 mice …

Mounting attention is being focused on the canonical Wnt signaling pathway which has
been implicated in the pathogenesis of autism in some our and other recent studies. The …

The hepatic central vein is a primary source of Wnt2, Wnt9b, and R‐spondin3. These
angiocrines activate ß‐catenin signaling to regulate hepatic metabolic zonation and …

Wnt/Ctnnb1 and Notch signaling play key roles in kidney development and epithelial cell
specification. Recent reports have suggested that these pathways are reactivated in …

Wnt signaling pathways constitute a group of signal transduction pathways that direct many
physiological processes, such as development, growth, and differentiation. Dysregulation of …

Maternal diet is associated with the development of metabolism-related and other non-
communicable diseases in offspring. Underlying mechanisms, functional profiles, and …

The development of an in vitro functional liver zonation model is a major issue to reproduce
physiological liver features. Oxygen concentration is one of the potential explanations of a …