Molecular biology and therapeutic targets of primitive tracheal tumors: focus on tumors derived by salivary glands and squamous cell carcinoma
Primary tracheal tumors are rare, constituting approximately 0.1–0.4% of malignant
diseases. Squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) account for …
diseases. Squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) account for …
Outcomes and prognostic factors in modern era management of major salivary gland cancer
Objectives There is a dearth of prospective evidence regarding cancer of the major salivary
glands. Outcomes and management of major salivary gland are based largely on …
glands. Outcomes and management of major salivary gland are based largely on …
Adjuvant radiotherapy versus concurrent chemoradiotherapy for the management of high‐risk salivary gland carcinomas
MJ Mifsud, T Tanvetyanon, JC Mccaffrey, KJ Otto… - Head & …, 2016 - Wiley Online Library
Background Given the aggressive behavior of advanced salivary malignancies, the purpose
of the current study was to explore the utility of adjuvant chemoradiotherapy (CRT) in this …
of the current study was to explore the utility of adjuvant chemoradiotherapy (CRT) in this …
Beyond surgical treatment in adenoid cystic carcinoma of the head and neck: A literature review
S Atallah, M Marc, A Schernberg, F Huguet… - Cancer management …, 2022 - Taylor & Francis
Introduction Adenoid cystic carcinoma (AdCC) is a rare tumour as it accounts for about 10%
of all salivary gland neoplasms. It occurs in all age groups with a predominance of women …
of all salivary gland neoplasms. It occurs in all age groups with a predominance of women …
Molecular targets in salivary gland cancers: a comprehensive genomic analysis of 118 mucoepidermoid carcinoma tumors
Introduction: Salivary gland carcinomas (SGC) are histologically diverse cancers and next-
generation sequencing (NGS) to identify key molecular targets is an important aspect in the …
generation sequencing (NGS) to identify key molecular targets is an important aspect in the …
A phase 2 trial of bortezomib followed by the addition of doxorubicin at progression in patients with recurrent or metastatic adenoid cystic carcinoma of the head and …
A Argiris, M Ghebremichael, B Burtness, RS Axelrod… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Bortezomib, an inhibitor of the 26S proteasome and NF‐κB, may have
antitumor activity in adenoid cystic carcinoma (ACC). Preclinical studies have shown …
antitumor activity in adenoid cystic carcinoma (ACC). Preclinical studies have shown …
Particle beam radiation therapy for adenoid cystic carcinoma of the nasal cavity and paranasal sinuses
W Hu, J Hu, Q Huang, J Gao, J Yang, X Qiu… - Frontiers in …, 2020 - frontiersin.org
Background: Sinonasal adenoid cystic carcinoma (SNACC) presents a challenge to
oncologists due to its complex anatomy and poor prognosis. Although radiation therapy …
oncologists due to its complex anatomy and poor prognosis. Although radiation therapy …
Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified
LG Sousa, K Wang, D Torman, BJ Binks, ML Rubin… - Cancer, 2022 - Wiley Online Library
Background Salivary duct carcinoma (SDC) and adenocarcinoma, not otherwise specified
(adeno‐NOS), are rare salivary gland cancers. Data on the efficacy of systemic therapy for …
(adeno‐NOS), are rare salivary gland cancers. Data on the efficacy of systemic therapy for …
[HTML][HTML] Genomic landscape of salivary gland tumors
S Kato, SK Elkin, M Schwaederle, BN Tomson… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Effective treatment options for advanced salivary gland tumors are lacking. To better
understand these tumors, we report their genomic landscape. We studied the molecular …
understand these tumors, we report their genomic landscape. We studied the molecular …
Salivary gland cancer: an update on present and emerging therapies
J Carlson, L Licitra, L Locati, D Raben… - American Society of …, 2013 - ascopubs.org
Malignant salivary gland tumors make up a small proportion of malignancies worldwide, yet
vary widely in terms of histology, patterns of spread, and recurrence. A better understanding …
vary widely in terms of histology, patterns of spread, and recurrence. A better understanding …