Alzheimer's disease (AD) is the most common form of neurodegenerative disease and is
considered the main cause of dementia worldwide. Genome-wide association studies …

Sialic acid (SA), as the ultimate epitope of polysaccharides, can act as a cap at the end of
polysaccharide chains to prevent their overextension. Sialylation is the enzymatic process of …

Systemic immunity supports lifelong brain function. Obesity posits a chronic burden on
systemic immunity. Independently, obesity was shown as a risk factor for Alzheimer's …

Apolipoprotein E4 (ApoE4) is the most recognized genetic risk factor for late-onset
Alzheimer's disease (LOAD), whereas ApoE2 reduces the risk for LOAD. The underlying …

Alzheimer's disease (AD) is a progressive illness, and early diagnosis and treatment can
help delay its progression. However, clinics still lack high‐throughput, low‐invasive, precise …

N-linked glycosylation represents a structurally diverse, complex, co-and posttranslational
protein modification that bridges metabolism and cellular signaling. Consequently, aberrant …

Low-concentration detection of sialic acid (SA) seems to be a promising method in early
cancer prognosis. In this work, a phosphorene-based field-effect-transistor (Ph-FET) device …

Polysialic acid (polySia) is a highly regulated polymer of sialic acid (Sia) with such potent
biophysical characteristics that when expressed drastically influences the interaction …

Sialic acid (SA) is overexpressed on cell membranes of tumor cells, and increased serum
SA concentration has been observed in tumor-bearing patients. Herein, a series of …

Glioblastoma (GBM) is the most common and aggressive adult brain cancer with an average
survival rate of around 15 months in patients receiving standard treatment. Oncolytic …