Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …

Hazardous chemicals in the environment and diet or their electrophilic metabolites can form
adducts with genomic DNA, which can lead to mutations and the initiation of cancer. In …

DNA adducts are believed to play a central role in the induction of cancer in cigarette
smokers and are proposed as being potential biomarkers of cancer risk. We have …

In human cells, the integrity of genetic information is constantly challenged by endogenous
and exogenous chemical agents that can induce DNA damage. To counteract the …

The use of electronic cigarettes (e‐cigarettes) has increased rapidly in the United States,
especially among high school students. e‐Cigarettes contain some recognized carcinogens …

Cigarette smoking is an established risk factor for oral cancer. The health effects of e-
cigarettes are still under investigation but may disturb oral cavity homeostasis and cause …

Cigarette smoking is an important source of human exposure to toxicants and carcinogens
and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a …

The measurement of DNA adducts, the covalent modifications of DNA upon the exposure to
the environmental and dietary genotoxicants and endogenously produced electrophiles …

Polycyclic aromatic hydrocarbons (PAHs) are recognized as potential etiological agents in
the development of oral cancer in smokers. In particular, benzo [a] pyrene (B [a] P) and …

The Multiethnic Cohort Study has demonstrated that the risk for lung cancer in cigarette
smokers among three ethnic groups is highest in Native Hawaiians, intermediate in Whites …