Islet transplantation holds significant promise as a curative approach for type 1 diabetes
(T1D). However, the transition of islet transplantation from the experimental phase to …

Type 1 Diabetes (T1D) is an autoimmune destruction of pancreatic beta cells. The
development of the Edmonton Protocol for islet transplantation in 2000 revolutionized T1D …

Aims The extracellular matrix (ECM) is fundamental for the normal endocrine functions of
pancreatic islet cells and plays key roles in the pathophysiology of type 2 diabetes. Here we …

Islet transplantation refers to the transfusion of healthy islet cells into the diabetic recipients
and reconstruction of their endogenous insulin secretion to achieve insulin independence. It …

Diabetes mellitus is a significant global public health challenge, with a rising prevalence and
associated morbidity and mortality. Cell therapy has evolved over time and holds great …

Diabetes is a complex metabolic disease and islet transplantation is a promising approach
for the treatment of diabetes. Unfortunately, the transplanted islets at the subcutaneous site …

It is now understood that islet transplantation serves as a β-cell replacement therapy for type
1 diabetes. Many factors impact the survival of transplanted islets, especially those related to …

Islet transplantation may be the most efficient therapeutic technique for patients with type 1
diabetes mellitus (T1DM). However, the clinical application of this method is faced with …

Islet transplantation is a curative treatment for patients suffering from type 1 diabetes and
has the potential to replace current treatment strategies involving the exogenous …

目的探讨间充质干细胞(MSC) 包裹胰岛对胰岛移植即刻经血液介导的炎症反应(IBMIR) 的影响.
方法将经示踪剂标记的MSC 与人胰岛放入超低吸附培养皿, 间隔0.5 h 吹打混匀2 次 …