Liver resection causes marked perfusion alterations in the liver remnant both on the organ
scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level) …

Background & Aims Despite improvements in medical and surgical techniques, post-
hepatectomy liver failure (PHLF) remains the leading cause of postoperative death. High …

The cardiovascular system plays a key role in the transport of nutrients, ensuring a
continuous supply of all cells of the body with the metabolites necessary for life. The blood …

Hepatic venous pressure gradient (HVPG) is a widely employed surrogate of portal pressure
gradient (PPG) in the diagnosis of portal hypertension (PHT). However, little is known about …

Backgroud The regenerative capacity of the liver is crucial for the host to survive after
serious hepatic injuries, tumor resection, or living donor liver transplantation. Panax …

Measurement of hepatic venous pressure gradient (HVPG) is currently widely adopted to
provide an estimate of portal pressure gradient (PPG) in the diagnosis and treatment of …

Objective: Cirrhosis is the common end stage of any given chronic liver disease, developing
after persistent destruction and regeneration of parenchymal liver cells. The associated …

The function of the liver depends critically on its blood supply. Numerous in silico models
have been developed to study various aspects of the hepatic circulation, including not only …

Recently a lumped-parameter model of the cardiovascular system was proposed to simulate
the hemodynamics response to partial hepatectomy and evaluate the risk of portal …

Hepatic venous pressure gradient (HVPG) is a hemodynamic index widely used for
evaluating the severity of portal hypertension. Theoretically, HVPG can be measured in any …