Recent developments in the immunopathology of COVID‐19

H Zhang, Y Sun, Y Wang, D Yazici, D Azkur, I Ogulur… - Allergy, 2023 - Wiley Online Library
There has been an important change in the clinical characteristics and immune profile of
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …

[HTML][HTML] Cellular and functional heterogeneity of the airway epithelium

JD Davis, TP Wypych - Mucosal immunology, 2021 - Elsevier
The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

[HTML][HTML] The role of oral microbiome in respiratory health and diseases

JL Pathak, Y Yan, Q Zhang, L Wang, L Ge - Respiratory Medicine, 2021 - Elsevier
The oral cavity (mouth) has various microbial habitats, including, teeth, gingival sulcus,
gingiva, tongue, inner cheek, hard palate, and soft palate. The human oral cavity houses the …

The role of glucocorticoids in inflammatory diseases

SD Reichardt, A Amouret, C Muzzi, S Vettorazzi… - Cells, 2021 - mdpi.com
For more than 70 years, glucocorticoids (GCs) have been a powerful and affordable
treatment option for inflammatory diseases. However, their benefits do not come without a …

[HTML][HTML] Lung microbiome and coronavirus disease 2019 (COVID-19): possible link and implications

S Khatiwada, A Subedi - Human microbiome journal, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly emerging disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease begins as an …

Alterations in the respiratory tract microbiome in COVID-19: current observations and potential significance

C Merenstein, FD Bushman, RG Collman - Microbiome, 2022 - Springer
SARS-CoV-2 infection causes COVID-19 disease, which can result in consequences
ranging from undetectable to fatal, focusing attention on the modulators of outcomes. The …

[HTML][HTML] Macrophage metabolic reprogramming during chronic lung disease

PP Ogger, AJ Byrne - Mucosal immunology, 2021 - Elsevier
Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …

Rheumatoid Arthritis–Specific Autoimmunity in the Lung Before and at the Onset of Disease

V Joshua, M Loberg Haarhaus… - Arthritis & …, 2023 - Wiley Online Library
Objective The lung is implicated as a site for breach of tolerance prior to onset of
seropositive rheumatoid arthritis (RA). To substantiate this, we investigated lung‐resident B …

[HTML][HTML] Probiotics, their extracellular vesicles and infectious diseases

AP Domínguez Rubio, CL D'Antoni, M Piuri… - Frontiers in …, 2022 - frontiersin.org
Probiotics have been shown to be effective against infectious diseases in clinical trials, with
either intestinal or extraintestinal health benefits. Even though probiotic effects are strain …

The respiratory microbiome in chronic hypersensitivity pneumonitis is distinct from that of idiopathic pulmonary fibrosis

R Invernizzi, BG Wu, J Barnett, P Ghai… - American Journal of …, 2021 - atsjournals.org
Rationale: Chronic hypersensitivity pneumonitis (CHP) is a condition that arises after
repeated exposure and sensitization to inhaled antigens. The lung microbiome is …