Recent findings in the genetics and epigenetics of asthma and allergy

M Kabesch, J Tost - Seminars in immunopathology, 2020 - Springer
In asthma and allergy genetics, a trend towards a few main topics developed over the last 2
years. First, a number of studies have been published recently which focus on overlapping …

A survey of gene prioritization tools for Mendelian and complex human diseases

O Zolotareva, M Kleine - Journal of integrative bioinformatics, 2019 - degruyter.com
Modern high-throughput experiments provide us with numerous potential associations
between genes and diseases. Experimental validation of all the discovered associations, let …

The new version of the ANDDigest tool with improved AI-based short names recognition

TV Ivanisenko, PS Demenkov, NA Kolchanov… - International Journal of …, 2022 - mdpi.com
The body of scientific literature continues to grow annually. Over 1.5 million abstracts of
biomedical publications were added to the PubMed database in 2021. Therefore …

ANDDigest: a new web-based module of ANDSystem for the search of knowledge in the scientific literature

TV Ivanisenko, OV Saik, PS Demenkov… - BMC …, 2020 - Springer
Background The rapid growth of scientific literature has rendered the task of finding relevant
information one of the critical problems in almost any research. Search engines, like Google …

Bioinformatic reconstruction and analysis of gene networks related to glucose variability in diabetes and its complications

OV Saik, VV Klimontov - International Journal of Molecular Sciences, 2020 - mdpi.com
Glucose variability (GV) has been recognized recently as a promoter of complications and
therapeutic targets in diabetes. The aim of this study was to reconstruct and analyze gene …

[HTML][HTML] Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID …

VA Ivanisenko, EV Gaisler, NV Basov, AD Rogachev… - Scientific Reports, 2022 - nature.com
Metabolomic analysis of blood plasma samples from COVID-19 patients is a promising
approach allowing for the evaluation of disease progression. We performed the …

A new version of the ANDSystem tool for automatic extraction of knowledge from scientific publications with expanded functionality for reconstruction of associative …

VA Ivanisenko, PS Demenkov, TV Ivanisenko… - BMC …, 2019 - Springer
Background Consideration of tissue-specific gene expression in reconstruction and analysis
of molecular genetic networks is necessary for a proper description of the processes …

[HTML][HTML] Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins

EA Antropova, TM Khlebodarova… - Vavilov Journal of …, 2022 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a risk factor that leads to hepatocellular carcinoma (HCC)
development. Epigenetic changes are known to play an important role in the molecular …

Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects

O Zolotareva, OV Saik, C Königs, EY Bragina… - Scientific reports, 2019 - nature.com
Asthma and hypertension are complex diseases coinciding more frequently than expected
by chance. Unraveling the mechanisms of comorbidity of asthma and hypertension is …

Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem

OV Saik, VV Nimaev, DB Usmonov, PS Demenkov… - BMC medical …, 2019 - Springer
Background Currently, more than 150 million people worldwide suffer from lymphedema. It
is a chronic progressive disease characterized by high-protein edema of various parts of the …