Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Curcumin, the golden spice in treating cardiovascular diseases

H Li, A Sureda, HP Devkota, V Pittalà, D Barreca… - Biotechnology …, 2020 - Elsevier
Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

Protective effects of curcumin against doxorubicin-induced toxicity and resistance: A review

M Mohajeri, A Sahebkar - Critical reviews in oncology/hematology, 2018 - Elsevier
Doxorubicin (DOX)-induced toxicity and resistance are major obstacles in chemotherapeutic
approaches. Despite effective in the treatment of numerous malignancies, some clinicians …

[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity

M Ashrafizadeh, A Zarrabi, F Hashemi, A Zabolian… - Pharmaceutics, 2020 - mdpi.com
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

The cardioprotective effects of nano‐curcumin against doxorubicin‐induced cardiotoxicity: A systematic review

H Moutabian, R Ghahramani‐Asl, T Mortezazadeh… - Biofactors, 2022 - Wiley Online Library
Although the chemotherapeutic drug, doxorubicin, is commonly used to treat various
malignant tumors, its clinical use is restricted because of its toxicity especially cardiotoxicity …

[HTML][HTML] Antidotal or protective effects of Curcuma longa (turmeric) and its active ingredient, curcumin, against natural and chemical toxicities: A review

A Hosseini, H Hosseinzadeh - Biomedicine & pharmacotherapy, 2018 - Elsevier
Curcuma longa is a rhizomatous perennial herb that belongs to the family Zingiberaceae,
native to South Asia and is commonly known as turmeric. It is used as herbal remedy due to …

Polyphenols, autophagy and doxorubicin-induced cardiotoxicity

S Shabalala, CJF Muller, J Louw, R Johnson - Life sciences, 2017 - Elsevier
Doxorubicin is a highly effective, first line chemotherapeutic agent used in the management
of hematological and solid tumors. The effective use of doxorubicin in cancer therapy has …

Curcumin as a potential protective compound against cardiac diseases

S Jiang, J Han, T Li, Z Xin, Z Ma, W Di, W Hu… - Pharmacological …, 2017 - Elsevier
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-
known bioactive compound derived from the active ingredient of turmeric (Curcuma longa) …

Stattic ameliorates the cecal ligation and puncture-induced cardiac injury in septic mice via IL-6-gp130-STAT3 signaling pathway

S Imbaby, Y Hattori - Life Sciences, 2023 - Elsevier
Aim Sepsis-induced cardiac dysfunction is the leading cause of higher morbidity and
mortality with poor prognosis in septic patients. Our recent previous investigation provides …

Curcumin attenuates doxorubicin-induced cardiotoxicity via suppressing oxidative stress and preventing mitochondrial dysfunction mediated by 14-3-3γ

H He, Y Luo, Y Qiao, Z Zhang, D Yin, J Yao, J You… - Food & Function, 2018 - pubs.rsc.org
Doxorubicin (Dox) induces cardiotoxicity, thereby limiting its clinical application for
chemotherapy of cancer. The mechanism of cardiotoxicity includes the production of excess …