Assessment of prophylactic carbapenem antibiotics administration for severe acute pancreatitis: an updated systematic review and meta-analysis

D Guo, W Dai, J Shen, M Zhang, Y Shi, K Jiang, L Guo - Digestion, 2022 - karger.com
Background: The effectiveness of prophylactic antibiotics in severe acute pancreatitis (SAP)
remains a debatable issue. This meta-analysis aimed to determine the efficacy of …

Macrophage‐Biomimetic Nanoplatform‐Based Therapy for Inflammation‐Associated Diseases

Y Qu, B Chu, J Li, H Deng, T Niu, Z Qian - Small Methods, 2023 - Wiley Online Library
Inflammation‐associated diseases are very common clinically with a high incidence;
however, there is still a lack of effective treatments. Cell‐biomimetic nanoplatforms have led …

Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

L Yang, F Ye, J Liu, DJ Klionsky, D Tang, R Kang - Autophagy, 2023 - Taylor & Francis
Acute pancreatitis (AP) is an abdominal inflammatory disease initiated by damaged
pancreatic acinar cells and developed by systemic inflammation. SQSTM1 (sequestosome …

EASY‐APP: An artificial intelligence model and application for early and easy prediction of severity in acute pancreatitis

B Kui, J Pintér, R Molontay, M Nagy… - Clinical and …, 2022 - Wiley Online Library
Background Acute pancreatitis (AP) is a potentially severe or even fatal inflammation of the
pancreas. Early identification of patients at high risk for developing a severe course of the …

Extracellular vesicle ITGAM and ITGB2 mediate severe acute pancreatitis-related acute lung injury

Q Hu, S Zhang, Y Yang, J Li, H Kang, W Tang… - ACS …, 2023 - ACS Publications
Integrins expressed on extracellular vesicles (EVs) secreted by various cancers are reported
to mediate the organotropism of these EVs. Our previous experiment found that pancreatic …

Causal link between gut microbiota and four types of pancreatitis: a genetic association and bidirectional Mendelian randomization study

K Wang, X Qin, T Ran, Y Pan, Y Hong, J Wang… - Frontiers in …, 2023 - frontiersin.org
Background A number of recent observational studies have indicated a correlation between
the constitution of gut microbiota and the incidence of pancreatitis. Notwithstanding …

Early plasmapheresis among patients with hypertriglyceridemia–associated acute pancreatitis

L Cao, Y Chen, S Liu, W Huang, D Wu… - JAMA Network …, 2023 - jamanetwork.com
Importance The incidence of hypertriglyceridemia–associated acute pancreatitis (HTG-AP)
is increasing. Plasmapheresis is theoretically effective in removing triglyceride from plasma …

Gut dysbiosis in pancreatic diseases: A causative factor and a novel therapeutic target

T Zhang, G Gao, HA Sakandar, LY Kwok, Z Sun - Frontiers in Nutrition, 2022 - frontiersin.org
Pancreatic-related disorders such as pancreatitis, pancreatic cancer, and type 1 diabetes
mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even …

[HTML][HTML] A microRNA checkpoint for Ca2+ signaling and overload in acute pancreatitis

W Du, G Liu, N Shi, D Tang, PE Ferdek… - Molecular Therapy, 2022 - cell.com
Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its
pathogenesis features multiple deleterious amplification loops dependent on translation …

Causal associations between modifiable risk factors and pancreatitis: A comprehensive Mendelian randomization study

X Mao, S Mao, H Sun, F Huang, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Background The pathogenesis of pancreatitis involves diverse environmental risk factors,
some of which have not yet been clearly elucidated. This study systematically investigated …