Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

Wound is defined as any injury to the body such as damage to the epidermis of the skin and
disturbance to its normal anatomy and function. Since ancient times, the importance of …

The ecological community of microorganisms in/on humans, termed the microbiome, is vital
for sustaining homeostasis. While culture-independent techniques have revealed the role of …

Each year, millions of individuals suffer from a non-healing wound, abnormal scarring, or
injuries accompanied by an infection. For these cases, scientists are searching for new …

The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …

In recent years, the incidence of infected wounds is steadily increasing, and so is the clinical
as well as economic interest in effective therapies. These combine reduction of pathogen …

Chronic wounds represent a large and growing disease burden. Infection and biofilm
formation are two of the leading impediments of wound healing, suggesting an important …

Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …

The treatment and management of chronic wounds presents a massive financial burden for
global health care systems, with significant and disturbing consequences for the patients …

The acidic pH of healthy skin changes during wound healing due to the exposure of the
inner dermal and subcutaneous tissue and due to the potential colonization of pathogenic …