A GPR174–CCL21 module imparts sexual dimorphism to humoral immunity
Humoral immune responses to immunization and infection and susceptibilities to antibody-
mediated autoimmunity are generally lower in males,–. However, the mechanisms …
mediated autoimmunity are generally lower in males,–. However, the mechanisms …
Oxysterols: old tale, new twists
Oxysterols have long been known for their important role in cholesterol homeostasis, where
they are involved in both transcriptional and posttranscriptional mechanisms for controlling …
they are involved in both transcriptional and posttranscriptional mechanisms for controlling …
[HTML][HTML] A review of vaccine effects on women in light of the COVID-19 pandemic
WH Chang - Taiwanese Journal of Obstetrics and Gynecology, 2020 - Elsevier
The pandemic situation triggered by the spread of COVID-19 has caused great harm
worldwide. More than six million people have been infected, and more than 360,000 of them …
worldwide. More than six million people have been infected, and more than 360,000 of them …
The chemoattractant receptor Ebi2 drives intranodal naive CD4+ T cell peripheralization to promote effective adaptive immunity
Lymph nodes (LNs) play critical roles in adaptive immunity by concentrating in one location
the antigens, antigen-presenting cells, and antigen-responsive lymphocytes involved in …
the antigens, antigen-presenting cells, and antigen-responsive lymphocytes involved in …
EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture
T Yi, JG Cyster - Elife, 2013 - elifesciences.org
Splenic dendritic cells (DCs) present blood-borne antigens to lymphocytes to promote T cell
and antibody responses. The cues involved in positioning DCs in areas of antigen exposure …
and antibody responses. The cues involved in positioning DCs in areas of antigen exposure …
Gut-inhabiting Clostridia build human GPCR ligands by conjugating neurotransmitters with diet-and human-derived fatty acids
FY Chang, P Siuti, S Laurent, T Williams… - Nature …, 2021 - nature.com
Human physiology is regulated by endogenous signalling compounds, including fatty acid
amides (FAAs), chemical mimics of which are made by bacteria. The molecules produced by …
amides (FAAs), chemical mimics of which are made by bacteria. The molecules produced by …
Anti-microbial functions of group 3 innate lymphoid cells in gut-associated lymphoid tissues are regulated by G-protein-coupled receptor 183
The intestinal tract is constantly exposed to various stimuli. Group 3 innate lymphoid cells
(ILC3s) reside in lymphoid organs and in the intestinal tract and are required for immunity to …
(ILC3s) reside in lymphoid organs and in the intestinal tract and are required for immunity to …
Effects of oxysterols on immune cells and related diseases
Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …
several cells, organs, and systems in the body. Oxysterols also have an influence on the …
Maternal antibodies inhibit neonatal and infant responses to vaccination by shaping the early-life B cell repertoire within germinal centers
M Vono, CS Eberhardt, F Auderset, B Mastelic-Gavillet… - Cell reports, 2019 - cell.com
Maternal antibodies (MatAbs) protect offspring from infections but limit their responses to
vaccination. The mechanisms of this inhibition are still debated. Using murine early-life …
vaccination. The mechanisms of this inhibition are still debated. Using murine early-life …
[HTML][HTML] Diverse immunoregulatory roles of oxysterols—the oxidized cholesterol metabolites
C Choi, DK Finlay - Metabolites, 2020 - mdpi.com
Intermediates of both cholesterol synthesis and cholesterol metabolism can have diverse
roles in the control of cellular processes that go beyond the control of cholesterol …
roles in the control of cellular processes that go beyond the control of cholesterol …