Impact of extent of resection for recurrent glioblastoma on overall survival

O Bloch, SJ Han, S Cha, MZ Sun, MK Aghi… - Journal of …, 2012 - thejns.org
Object Extent of resection (EOR) has been shown to be an important prognostic factor for
survival in patients undergoing initial resection of glioblastoma (GBM), but the significance of …

Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas

MJ van den Bent, JS Wefel, D Schiff… - The lancet …, 2011 - thelancet.com
Although low-grade gliomas (LGG) have a less aggressive course than do high-grade
gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour …

Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases

L Capelle, D Fontaine, E Mandonnet… - Journal of …, 2013 - thejns.org
Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Glioma extent of resection and its impact on patient outcome

N Sanai, MS Berger - Neurosurgery, 2008 - journals.lww.com
OBJECTIVE: There is still no general consensus in the literature regarding the role of extent
of glioma resection in improving patient outcome. Although the importance of resection in …

Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up

L Douw, M Klein, SSAA Fagel… - The Lancet …, 2009 - thelancet.com
Background Our previous study on cognitive functioning among 195 patients with low-grade
glioma (LGG) a mean of 6 years after diagnosis suggested that the tumour itself, rather than …

New concepts in the management of diffuse low-grade glioma: proposal of a multistage and individualized therapeutic approach

H Duffau, L Taillandier - Neuro-oncology, 2015 - academic.oup.com
Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-
grade glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

Epileptic seizures in diffuse low-grade gliomas in adults

J Pallud, E Audureau, M Blonski, N Sanai, L Bauchet… - Brain, 2014 - academic.oup.com
Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas

C Houillier, X Wang, G Kaloshi, K Mokhtari… - Neurology, 2010 - AAN Enterprises
Objectives: Recent studies have shown that IDH1 and IDH2 mutations occur frequently in
gliomas, including low-grade gliomas. However, their impact on the prognosis and …

Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up

H Duffau - Acta neurochirurgica, 2016 - Springer
Background Total or subtotal surgical resection of WHO grade II glioma (diffuse low-grade
glioma, DLGG) can significantly increase survival. Moreover, a supratotal resection, ie, an …

Guidelines on management of low‐grade gliomas: report of an EFNS–EANO* Task Force

R Soffietti, BG Baumert, L Bello… - European journal of …, 2010 - Wiley Online Library
Background: Diffuse infiltrative low‐grade gliomas of the cerebral hemispheres in the adult
are a group of tumors with distinct clinical, histological and molecular characteristics, and …