Intraoperative confocal microscopy in the visualization of 5-aminolevulinic acid fluorescence in low-grade gliomas
N Sanai, LA Snyder, NJ Honea, SW Coons… - Journal of …, 2011 - thejns.org
Object Greater extent of resection (EOR) for patients with low-grade glioma (LGG)
corresponds with improved clinical outcome, yet remains a central challenge to the …
corresponds with improved clinical outcome, yet remains a central challenge to the …
[HTML][HTML] Operative techniques for gliomas and the value of extent of resection
N Sanai, MS Berger - Neurotherapeutics, 2009 - Elsevier
Refinement of neurosurgical technique has enabled safer operations with more aggressive
outcomes. One cornerstone of modern-day practice is the utilization of intraoperative …
outcomes. One cornerstone of modern-day practice is the utilization of intraoperative …
Sodium fluorescein–guided resection under the YELLOW 560 nm surgical microscope filter in malignant brain tumor surgery—a feasibility study
KM Schebesch, M Proescholdt, J Höhne… - Acta …, 2013 - Springer
Objective In glioma surgery, the extent of resection (EOR) is one important predictor of
progression-free survival. In 2006, fluorescence-guided surgery using 5-aminolevulinic acid …
progression-free survival. In 2006, fluorescence-guided surgery using 5-aminolevulinic acid …
Identifying preoperative language tracts and predicting postoperative functional recovery using HARDI q-ball fiber tractography in patients with gliomas
OBJECT Diffusion MRI has uniquely enabled in vivo delineation of white matter tracts, which
has been applied to the segmentation of eloquent pathways for intraoperative mapping. The …
has been applied to the segmentation of eloquent pathways for intraoperative mapping. The …
State-of-the-art imaging for glioma surgery
N Verburg, PC de Witt Hamer - Neurosurgical review, 2021 - Springer
Diffuse gliomas are infiltrative primary brain tumors with a poor prognosis despite
multimodal treatment. Maximum safe resection is recommended whenever feasible. The …
multimodal treatment. Maximum safe resection is recommended whenever feasible. The …
Central nervous system cancers
Primary and metastatic tumors of the central nervous system are a heterogeneous group of
neoplasms with varied outcomes and management strategies. Recently, improved survival …
neoplasms with varied outcomes and management strategies. Recently, improved survival …
Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary
identification and complete resection of the tumor are essential for glioma removal during …
identification and complete resection of the tumor are essential for glioma removal during …
Functional preoperative and intraoperative mapping and monitoring: increasing safety and efficacy in glioma surgery
Greater extent of resection (EOR) of low-grade gliomas is associated with improved survival.
Proximity to eloquent cortical regions often limits resectability and elevates the risk of …
Proximity to eloquent cortical regions often limits resectability and elevates the risk of …
Detection of glioma infiltration at the tumor margin using quantitative stimulated Raman scattering histology
In the management of diffuse gliomas, the identification and removal of tumor at the
infiltrative margin remains a central challenge. Prior work has demonstrated that …
infiltrative margin remains a central challenge. Prior work has demonstrated that …
Intraoperative stimulation techniques for functional pathway preservation and glioma resection
N Sanai, MS Berger - Neurosurgical focus, 2010 - thejns.org
Although a primary tenet of neurosurgical oncology is that survival can improve with greater
tumor resection, this principle must be tempered by the potential for functional loss following …
tumor resection, this principle must be tempered by the potential for functional loss following …