NAD+ homeostasis in health and disease

E Katsyuba, M Romani, D Hofer, J Auwerx - Nature metabolism, 2020 - nature.com
The conceptual evolution of nicotinamide adenine dinucleotide (NAD+) from being seen as
a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and …

EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication

A Goette, JM Kalman, L Aguinaga, J Akar… - Heart …, 2017 - heartrhythmjournal.com
The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: definition, characterization, and clinical implication

A Goette, JM Kalman, L Aguinaga, J Akar… - Ep …, 2016 - academic.oup.com
The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

DG Allen, NP Whitehead… - Physiological …, 2016 - journals.physiology.org
Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

AWB Joe, L Yi, A Natarajan, F Le Grand, L So… - Nature cell …, 2010 - nature.com
Efficient tissue regeneration is dependent on the coordinated responses of multiple cell
types. Here, we describe a new subpopulation of fibro/adipogenic progenitors (FAPs) …

[HTML][HTML] Histology, composition, and quality traits of chicken Pectoralis major muscle affected by wooden breast abnormality

F Soglia, S Mudalal, E Babini, M Di Nunzio, M Mazzoni… - Poultry science, 2016 - Elsevier
Only a few years ago, the poultry industry began to face a recent abnormality in breast meat,
known as wooden breast, which frequently overlaps with white striping. This study aimed to …

Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells

AJ Earle, TJ Kirby, GR Fedorchak, P Isermann… - Nature materials, 2020 - nature.com
Mutations in the LMNA gene, which encodes the nuclear envelope (NE) proteins lamins A/C,
cause Emery–Dreifuss muscular dystrophy, congenital muscular dystrophy and other …

Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing

F Chemello, Z Wang, H Li… - Proceedings of the …, 2020 - National Acad Sciences
Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of
degeneration and regeneration of multinucleated myofibers and pathological activation of a …

CRISPR-mediated genome editing restores dystrophin expression and function in mdx mice

L Xu, KH Park, L Zhao, J Xu, M El Refaey, Y Gao… - Molecular Therapy, 2016 - cell.com
Duchenne muscular dystrophy (DMD) is a degenerative muscle disease caused by genetic
mutations that lead to the disruption of dystrophin in muscle fibers. There is no curative …

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

B Malecova, S Gatto, U Etxaniz, M Passafaro… - Nature …, 2018 - nature.com
Fibro-adipogenic progenitors (FAPs) are currently defined by their anatomical position,
expression of non-specific membrane-associated proteins, and ability to adopt multiple …