Sepsis, an innate immunological response of systemic inflammation to infection, is a
growing problem worldwide with a relatively high mortality rate. Immediate treatment is …

BACKGROUND: Rhinovirus-induced acute asthma is the most frequent trigger for asthma
exacerbations. OBJECTIVE: We assessed which inflammatory mediators were released …

Background and Aims: The gold standard treatment of chronic hepatitis C (CHC) is
combined pegylated interferon and ribavirin. Considering side effects and treatment cost …

Background High baseline levels of IP-10 predict a slower first phase decline in HCV RNA
and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C …

Chronic infection with the hepatitis C virus, a noncytopathic hepatotropic RNA virus, affects
over 170 million people worldwide. In the majority of cases, neither the early innate immune …

Chemokines produced in the liver during hepatitis C virus (HCV) infection induce migration
of activated T cells from the periphery to infected parenchyma. The milieu of chemokines …

Hepatitis C virus (HCV) infection induces the endogenous interferon (IFN) system in the liver
in some but not all patients with chronic hepatitis C (CHC). Patients with a pre‐activated IFN …

The interferon sensitivity determining region (ISDR) of the hepatitis C virus (HCV) and T‐
helper type 1 and type 2 (Th1/Th2) ratio were analyzed along with other host and viral …

High systemic levels of interferon‐gamma‐inducible protein 10 kDa (IP‐10) at onset of
combination therapy for chronic hepatitis C virus (HCV) infection predict poor outcome, but …

Recent genome-wide association studies (GWAS) have identified genetic variations near
the IL28B gene which are strongly associated with spontaneous and treatment-induced …