Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver
disease. Non-alcoholic steatohepatitis (NASH) is a more severe form of NAFLD and causes …

The mechanism of the interferon-alpha (IFNα)–induced antiviral response is not completely
understood. We recently examined the transcriptional response to IFNα in uninfected …

Serum levels of the interferon (IFN)-stimulated chemokine CXCL10 are increased during
chronic HCV infection and associate with outcome of IFN-based therapy. Elevated levels of …

We previously reported that infection of different mouse strains with a recombinant HSV-1
expressing IL-2 (HSV-IL-2) caused CNS demyelination. Histologic examination of infected IL …

Abstract Background Hepatitis C virus (HCV) is one of the major causes of liver cancer. The
single nucleotide polymorphisms within the IFNL3 gene, which encodes interferon (IFN)-λ 3 …

The hepatitis C virus infection represents an important public health problem and is
associated with various hepatic and extrahepatic manifestations. Symptoms outside of the …

Background In mouse models, natural killer (NK) cells have been shown to exert anti-fibrotic
activity via killing of activated hepatic stellate cells (HSC). Chemokines and chemokine …

Interferon lambda 4 (IFN-λ4) is a novel type-III interferon that can be generated only in
individuals carrying a ΔG frame-shift allele of an exonic genetic variant (rs368234815 …

Background: Dendritic cell (DC) defects may contribute to chronicity in hepatitis C virus
(HCV) infection and determine response to PEG–interferon and ribavirin therapy via poor T …

This study aims to evaluate the effects of photobiomodulation (PBM) on human monocytes,
assessing the oxidative burst and ultimate fungicidal potential of these cells, as well as the …