Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

Donor organ shortage still remains a serious obstacle for the access of wait-list patients to
kidney transplantation, the best treatment for End-Stage Kidney Disease (ESKD). To expand …

Hypothermic machine perfusion (HMP) is a preferable measure to preserve kidneys from
donation after cardiac death (DCD), while the current standard perfusate is imperfect. We …

Normothermic machine perfusion of kidneys: current strategie... : Current Opinion in Organ
Transplantation Normothermic machine perfusion of kidneys: current strategies and future …

Background. Extracellular vesicles (EVs) are tissue-specific particles released by cells
containing valuable diagnostic information in the form of various biomolecules. The …

Background. Normothermic machine perfusion (NMP) provides a promising strategy for
preservation and conditioning of marginal organ grafts. However, at present, high logistic …

Background. Hypothermic oxygenated perfusion (HOPE) improves outcomes of marginal
liver grafts. However, to date, no preservation solution exists for both static cold storage …

Renal ischemia-reperfusion is a common cause of acute kidney injury leading to significant
morbidity and mortality. There are no effective treatments available in clinical practice. This …

In transplantation, hypothermic machine perfusion (HMP) has been shown to be superior to
static cold storage (SCS) in terms of functional outcomes. Ex vivo machine perfusion offers …

Abstract Purpose of Review Normothermic machine perfusion (NMP) is a promising new tool
in kidney transplantation to improve the outcome of marginal donor kidney transplantation …