[HTML][HTML] Adipokines as clinically relevant therapeutic targets in obesity
M Würfel, M Blüher, M Stumvoll, T Ebert, P Kovacs… - Biomedicines, 2023 - mdpi.com
Adipokines provide an outstanding role in the comprehensive etiology of obesity and may
link adipose tissue dysfunction to further metabolic and cardiovascular complications …
link adipose tissue dysfunction to further metabolic and cardiovascular complications …
[HTML][HTML] The role of selected adipocytokines in ovarian cancer and endometrial cancer
S Stępień, P Olczyk, J Gola, K Komosińska-Vassev… - Cells, 2023 - mdpi.com
Due to their multidirectional influence, adipocytokines are currently the subject of numerous
intensive studies. Significant impact applies to many processes, both physiological and …
intensive studies. Significant impact applies to many processes, both physiological and …
[HTML][HTML] The role of chemerin in metabolic and cardiovascular disease: a literature review of its physiology and pathology from a nutritional perspective
Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …
It also induces inflammation and affects insulin signaling, steroidogenesis and …
[HTML][HTML] Chemerin forms: their generation and activity
Chemerin is the product of the RARRES2 gene which is secreted as a precursor of 143
amino acids. That precursor is inactive, but proteases from the coagulation and fibrinolytic …
amino acids. That precursor is inactive, but proteases from the coagulation and fibrinolytic …
[HTML][HTML] Molecular pharmacology of inflammation resolution in atherosclerosis
S Kotlyarov, A Kotlyarova - International Journal of Molecular Sciences, 2022 - mdpi.com
Atherosclerosis is one of the most important problems of modern medicine as it is the
leading cause of hospitalizations, disability, and mortality. The key role in the development …
leading cause of hospitalizations, disability, and mortality. The key role in the development …
[HTML][HTML] Understanding the role of chemerin in the pathophysiology of pre-eclampsia
K Pankiewicz, T Issat - Antioxidants, 2023 - mdpi.com
Chemerin is a multifaceted adipokine that is involved in multiple biological processes,
including inflammation, angiogenesis, adipogenesis, and energy metabolism, as well as …
including inflammation, angiogenesis, adipogenesis, and energy metabolism, as well as …
[HTML][HTML] Role of chemerin in cardiovascular diseases
(1) Background: Obesity is closely connected to the pathophysiology of cardiovascular
diseases (CVDs). Excess fat accumulation is associated with metabolic malfunctions that …
diseases (CVDs). Excess fat accumulation is associated with metabolic malfunctions that …
Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin
AWC Man, Y Zhou, G Reifenberg, A Camp… - Cardiovascular …, 2023 - academic.oup.com
Aims Obesity is an epidemic that is a critical contributor to hypertension and other
cardiovascular diseases. Current paradigms suggest that endothelial nitric oxide synthase …
cardiovascular diseases. Current paradigms suggest that endothelial nitric oxide synthase …
[HTML][HTML] The regulatory roles of chemerin-chemokine-like receptor 1 axis in placental development and vascular remodeling during early pregnancy
Chemerin is an adipokine that regulates metabolism in pregnancy. An elevation of serum
chemerin level is associated with pregnancy complications. Consistently, we demonstrated …
chemerin level is associated with pregnancy complications. Consistently, we demonstrated …
[HTML][HTML] Structural basis of G protein–Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist
Chemokine-like receptor 1 (CMKLR1), also known as chemerin receptor 23 (ChemR23) or
chemerin receptor 1, is a chemoattractant G protein–coupled receptor (GPCR) that responds …
chemerin receptor 1, is a chemoattractant G protein–coupled receptor (GPCR) that responds …