Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

Conclusions: Loss of hepatocytes and increased ductular reaction are tightly associated with
monocyte-derived macrophage accumulation and represent the most prominent common …

This is the second European Crohn's and Colitis Organisation [ECCO] evidence-based
consensus on extraintestinal manifestations [EIMs] of inflammatory bowel disease [IBD] and …

Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis
(PSC), and IgG4-related sclerosing cholangitis (IgG4-SC) are the four main forms of …

Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease characterized by
inflammation and fibrosis of the bile ducts. Cholestasis may lead to hepatic inflammation and …

Background Primary sclerosing cholangitis (PSC) is a chronic progressive liver disease
leading to biliary fibrosis and cirrhosis. Cilofexor is a nonsteroidal farnesoid X receptor …

Primary sclerosing cholangitis (PSC) is an idiopathic chronic immune-mediated cholestatic
liver disease characterized by fibro-inflammatory bile duct strictures, progressive …

Background Liver cirrhosis is a significant yet largely preventable and underappreciated
cause of global health loss. This study aimed to profile the global and regional burdens of …

Primary sclerosing cholangitis is a rare chronic inflammatory disease affecting the bile ducts,
which can eventually result in bile duct strictures, cholestasis and cirrhosis. Patients are …

Primary sclerosing cholangitis (PSC) was declared one of the biggest unmet needs in
hepatology during ILC 2016 in Berlin. Since then, not much has changed unfortunately …