Mesenchymal stem cells improve rheumatoid arthritis progression by controlling memory T cell response

N Luque-Campos, RA Contreras-López… - Frontiers in …, 2019 - frontiersin.org
In the last years, mesenchymal stem cell (MSC)-based therapies have become an
interesting therapeutic opportunity for the treatment of rheumatoid arthritis (RA) due to their …

Role of immunological memory cells as a therapeutic target in multiple sclerosis

T Bose - Brain sciences, 2017 - mdpi.com
Pharmacological targeting of memory cells is an attractive treatment strategy in various
autoimmune diseases, such as psoriasis and rheumatoid arthritis. Multiple sclerosis is the …

Alterations in levels of CD28-/CD8+ suppressor cell precursor and CD45RO+/CD4+ memory T lymphocytes in the peripheral blood of multiple sclerosis patients

B Crucian, P Dunne, H Friedman… - Clinical Diagnostic …, 1995 - Am Soc Microbiol
A comprehensive peripheral blood immunophenotype analysis of 16 multiple sclerosis (MS)
patients was performed by three-color flow cytometric analysis, and the results were …

Direct demonstration of the infiltration of murine central nervous system by Pgp-1/CD44high CD45RBlow CD4+ T cells that induce experimental allergic …

R Zeine, T Owens - Journal of neuroimmunology, 1992 - Elsevier
In experimental allergic encephalomyelitis (EAE), autoimmune T cells infiltrate the central
nervous system (CNS) and initiate demyelinating pathology. We have used flow cytometry to …

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis

T Renno, R Zeine, JM Girard, S Gillani… - International …, 1994 - academic.oup.com
The cytokine effector status of CD4+ T cells from lymph nodes (LN) and the central nervous
system (CNS) of SJL/J mice immunized with autoantlgen in adjuvant for the induction of …

T-cell phenotypic profiles in the cerebrospinal fluid and peripheral blood of multiple sclerosis patients

R Scolozzi, A Boccafogli, MR Tola, L Vicentini… - Journal of the …, 1992 - Elsevier
Thirty-nine patients with clinically definite multiple sclerosis (MS) entered the study. Of 28
subjects with a relapsing-remitting course, 19 were classified in acute relapse, 9 in …

Impaired expression of tetraspanin 32 (TSPAN32) in memory T cells of patients with multiple sclerosis

MS Basile, E Mazzon, K Mangano, M Pennisi… - Brain Sciences, 2020 - mdpi.com
Tetraspanins are a conserved family of proteins involved in a number of biological
processes. We have previously shown that Tetraspanin-32 (TSPAN32) is significantly …

Effects of occupational metallic mercury vapour exposure on suppressor-inducer (CD4+ CD45RA+) T lymphocytes and CD57+ CD16+ natural killer cells

SH Park, S Araki, A Nakata, YH Kim, JA Park… - International archives of …, 2000 - Springer
Objectives: To examine the effects of metallic mercury vapour on the cellular and humoral
immune system. Methods: We measured T lymphocyte and natural killer (NK) cell …

CD5+ B cells and CD4− 8− T cells in neuroimmunological diseases

J Correale, E Mix, T Olsson, V Kostulas… - Journal of …, 1991 - Elsevier
Abstract Using 2-and 3-colour FACS analysis we found increased levels of fetal-type CD5+
B cells and CD4− 8− T cells in cerebrospinal fluid (CSF) of patients with multiple sclerosis …

Lymphocyte subsets in multiple sclerosis A study with two-colour fluorescence analysis

P Bongioanni, C Fioretti, R Vanacore, F Bianchi… - Journal of the …, 1996 - Elsevier
Multiple sclerosis (MS) is postulated to be an immunopathologically mediated disease. This
concept is supported by the finding of abnormally distributed peripheral blood T-cell subsets …